ID I6ASK3_9BACT Unreviewed; 770 AA.
AC I6ASK3;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Family 3 adenylate cyclase {ECO:0000313|EMBL:EIP97994.1};
GN ORFNames=OpiT1DRAFT_02444 {ECO:0000313|EMBL:EIP97994.1};
OS Opitutaceae bacterium TAV1.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=278956 {ECO:0000313|EMBL:EIP97994.1, ECO:0000313|Proteomes:UP000004921};
RN [1] {ECO:0000313|EMBL:EIP97994.1, ECO:0000313|Proteomes:UP000004921}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAV1 {ECO:0000313|EMBL:EIP97994.1,
RC ECO:0000313|Proteomes:UP000004921};
RX PubMed=22535930; DOI=10.1128/JB.00264-12;
RA Isanapong J., Goodwin L., Bruce D., Chen A., Detter C., Han J., Han C.S.,
RA Held B., Huntemann M., Ivanova N., Land M.L., Mavromatis K., Nolan M.,
RA Pati A., Pennacchio L., Pitluck S., Szeto E., Tapia R., Woyke T.,
RA Rodrigues J.L.;
RT "High-Quality Draft Genome Sequence of the Opitutaceae Bacterium Strain
RT TAV1, a Symbiont of the Wood-Feeding Termite Reticulitermes flavipes.";
RL J. Bacteriol. 194:2744-2745(2012).
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DR EMBL; JH660698; EIP97994.1; -; Genomic_DNA.
DR AlphaFoldDB; I6ASK3; -.
DR HOGENOM; CLU_000445_85_1_0; -.
DR Proteomes; UP000004921; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 494..633
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 84723 MW; 0BC53F90F0273EDB CRC64;
MSSLPATPAP SASDAGRITP QQKRRRWRGQ WLAVALLPLA LLWALFDTLG ALRTIEEETV
DWRFRWRGTL EAPVNVVYVD IDSQAVSELG NFPWNRDRFA TVCKALLAEA RVKAIGVDVL
MSEAGMPQVV NRAAWNRGNA ELGDFLFSEP PPPVVLAAAY MGAIRRDEEG NALPVEIPLA
GSMPADFPEQ PRWQGPDGLW KPAPHHGLID TLDNDTRIVP LFAPLPDGGN VLHLSLELAR
IWWGVPKEGV RIRDDRIDMV DEDGRPVRRI PLPGGQFLAI NWFSAWKAEG QNPRISFADV
HTYAGMLGSA DEAERAAAKE FFGQEGFRDA VVLIGATDPL MHDMATTSFD RHPVPKVGIY
GNVLKMLVAG RFLHHPPGWV VWVVTGMLGY LITKGFAGAA RERERVTALV LVLVYVALVF
VVFWRLDWVM PLAAPVGGAL SAGFAGLGVQ VVIERRQRNR LQGMFGSYVS PEVVRQLVES
GEEPKLGGVE EEITAYFSDV QMFASVSEKL TPTQLVELMN EYLGACADVV QAQGGTLDKF
VGDAVVAMFG APVPLPDHAH RACIAALRVQ QRLEAMRRQW ASETHRDWPA EVVGLRTRIG
LNSGRAVVGN MGSSARFNYT MMGDTVNLAA RLESAARQWG VFTLCTAETK AGCEAVEPGR
VVFRRLNNTV VKGRSQPVEI YEVVGLREQV SEETHECLQI FGVGLRCYNE RDWAGARAAF
RASARLEPHK PGEAPGVTLN PSLALLGMVG ELQTNPPWGD WDGSYRMREK
//
