ID   I6CGJ9_SHIFL            Unreviewed;       493 AA.
AC   I6CGJ9;
DT   05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2012, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Outer membrane protein tolC {ECO:0000313|EMBL:EIQ18641.1};
GN   Name=tolC {ECO:0000313|EMBL:EIQ18641.1};
GN   ORFNames=SFK315_3456 {ECO:0000313|EMBL:EIQ18641.1};
OS   Shigella flexneri K-315.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=766150 {ECO:0000313|EMBL:EIQ18641.1, ECO:0000313|Proteomes:UP000005407};
RN   [1] {ECO:0000313|EMBL:EIQ18641.1, ECO:0000313|Proteomes:UP000005407}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K-315 {ECO:0000313|EMBL:EIQ18641.1,
RC   ECO:0000313|Proteomes:UP000005407};
RA   Rasko D., Redman J., Daugherty S.C., Tallon L., Sadzewicz L., Jones K.,
RA   Santana-Cruz I., Liu X.;
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC       family. {ECO:0000256|ARBA:ARBA00007613}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EIQ18641.1}.
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DR   EMBL; AKMY01000063; EIQ18641.1; -; Genomic_DNA.
DR   AlphaFoldDB; I6CGJ9; -.
DR   SMR; I6CGJ9; -.
DR   PATRIC; fig|766150.3.peg.3363; -.
DR   Proteomes; UP000005407; Unassembled WGS sequence.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR   InterPro; IPR003423; OMP_efflux.
DR   InterPro; IPR010130; T1SS_OMP_TolC.
DR   NCBIfam; TIGR01844; type_I_sec_TolC; 1.
DR   PANTHER; PTHR30026; OUTER MEMBRANE PROTEIN TOLC; 1.
DR   PANTHER; PTHR30026:SF15; OUTER MEMBRANE PROTEIN TOLC; 1.
DR   Pfam; PF02321; OEP; 2.
DR   SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE   3: Inferred from homology;
KW   Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..493
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003702268"
FT   REGION          278..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        472..493
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   493 AA;  53755 MW;  C097AA37CD19A68D CRC64;
     MKKLLPILIG LSLSGFSSLS QAENLMQVYQ QARLSNPELR KSAADRDAAF EKINEARSPL
     LPQLGLGADY TYSNGYRDAN GINSNATSAS LQLTQSIFDM SKWRALTLQE KAAGIQDVTY
     QTDQQTLILN TATAYFNVLN AIDVLSYTQA QKEAIYRQLD QTTQRFNVGL VAITDVQNAR
     AQYDTVLANE VTARNNLDNA VEQLRQITGN YYPELAALNV ENFKTDKPQP VNALLKEAEK
     RNLSLLQARL SQDLAREQIR QAQDGHLPTL DLTASTGISD TSYSGSKTRG AAGTQYDDSN
     MGQNKVGLSF SLPIYQGGMV NSQVKQAQYN FVGASEQLES AHRSIVQTVR SSFNNINASI
     SSINAYKQAV VSAQSSLDAM EAGYSVGTRT IVDVLDATTT LYNAKQELAN ARYNYLINQL
     NIKSALGTLN EQDLLALNNA LSKPVSTNPE NVAPQTPEQN AIADGYAPDS PAPVVQQTSA
     RTTTSNGHNP FRN
//