ID   I6PCE8_FRAVE            Unreviewed;       397 AA.
AC   I6PCE8;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177};
DE            EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};
GN   Name=YUC11 {ECO:0000313|EMBL:AFG16919.1};
OS   Fragaria vesca (Woodland strawberry) (Potentilla vesca).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae;
OC   Fragaria.
OX   NCBI_TaxID=57918 {ECO:0000313|EMBL:AFG16919.1};
RN   [1] {ECO:0000313|EMBL:AFG16919.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Runner {ECO:0000313|EMBL:AFG16919.1};
RA   Liu H., Zhang L., Gao Q.-H., Duan K.;
RT   "Isolation and characterization of YUCCA family genes in woodland
RT   strawberry.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + indole-3-pyruvate + NADPH + O2 = (indol-3-yl)acetate +
CC         CO2 + H2O + NADP(+); Xref=Rhea:RHEA:34331, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16526,
CC         ChEBI:CHEBI:17640, ChEBI:CHEBI:30854, ChEBI:CHEBI:57783,
CC         ChEBI:CHEBI:58349; EC=1.14.13.168;
CC         Evidence={ECO:0000256|ARBA:ARBA00035920};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974,
CC         ECO:0000256|RuleBase:RU361177};
CC   -!- PATHWAY: Plant hormone metabolism; auxin biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004814}.
CC   -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183,
CC       ECO:0000256|RuleBase:RU361177}.
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DR   EMBL; JF922290; AFG16919.1; -; mRNA.
DR   RefSeq; NP_001266975.1; NM_001280046.1.
DR   AlphaFoldDB; I6PCE8; -.
DR   GeneID; 101306714; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0103075; F:indole-3-pyruvate monooxygenase activity; IEA:RHEA.
DR   GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0009851; P:auxin biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000960; Flavin_mOase.
DR   InterPro; IPR020946; Flavin_mOase-like.
DR   PANTHER; PTHR43539; FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220); 1.
DR   PANTHER; PTHR43539:SF77; INDOLE-3-PYRUVATE MONOOXYGENASE YUCCA10-RELATED; 1.
DR   Pfam; PF00743; FMO-like; 1.
DR   PIRSF; PIRSF000332; FMO; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE   2: Evidence at transcript level;
KW   Auxin biosynthesis {ECO:0000256|ARBA:ARBA00023070};
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU361177};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW   ECO:0000256|RuleBase:RU361177}; Membrane {ECO:0000256|SAM:Phobius};
KW   Monooxygenase {ECO:0000256|RuleBase:RU361177};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU361177}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   397 AA;  44148 MW;  2AEC081DC2549C48 CRC64;
     MENNVFGNYL VVIVGAGPSG IATSALLNSM SIPNIVFERE DCCASLWKKR SYDRLCLHLA
     KNFCSLPMMP HSFRTATFMS KDKFADYVDK YVTRFNVNPR YCHNVESALY EEANQKWKIE
     VKNTEVTDGV GSLQVYYADF LVIATGENSR PVTPELPGIE TFKGNVMHAQ DYKCGASFKD
     QNVLVVGCGN SGMEISNDLA ESGAHASIVV RSQVHVLSRE LVRLGMVLLD YLPMNIVDRF
     ILYLAKFSYG DLPSYGISPP VEGPFFFKAL TGKTPVIDRG TVKKIRSGKI KVFSGVETIR
     HNIVEFKNGS IQRVDAIVMA TGYRSVAHKW LKDYKVILDE NDKPKNKYPG HWKGEKGVYC
     VGFSGKGIPG ISFDSRAVAN DIHQILLVKT GNAAREV
//