ID I6WPB5_9LABR Unreviewed; 242 AA.
AC I6WPB5;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Cardiac muscle myosin heavy chain 6 alpha {ECO:0000313|EMBL:AFN28670.1};
DE Flags: Fragment;
GN Name=myh6 {ECO:0000313|EMBL:AFN28670.1};
OS Labrichthys unilineatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrichthys.
OX NCBI_TaxID=241306 {ECO:0000313|EMBL:AFN28670.1};
RN [1] {ECO:0000313|EMBL:AFN28670.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LuniA {ECO:0000313|EMBL:AFN28670.1};
RX PubMed=22744773; DOI=10.1093/sysbio/sys060;
RA Wainwright P.C., Smith W.L., Price S.A., Tang K.L., Sparks J.S.,
RA Ferry L.A., Kuhn K.L., Eytan R.I., Near T.J.;
RT "The evolution of pharyngognathy: a phylogenetic and functional appraisal
RT of the pharyngeal jaw key innovation in labroid fishes and beyond.";
RL Syst. Biol. 61:1001-1027(2012).
CC -!- FUNCTION: Muscle contraction. {ECO:0000256|ARBA:ARBA00037488}.
CC -!- SUBUNIT: Muscle myosin is a hexameric protein that consists of 2 heavy
CC chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2
CC regulatory light chain subunits (MLC-2).
CC {ECO:0000256|ARBA:ARBA00038612}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; JX189730; AFN28670.1; -; Genomic_DNA.
DR AlphaFoldDB; I6WPB5; -.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF11; MYOSIN-6; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 1..242
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFN28670.1"
FT NON_TER 242
FT /evidence="ECO:0000313|EMBL:AFN28670.1"
SQ SEQUENCE 242 AA; 26867 MW; 6F69EA56C3B11C8C CRC64;
KTVNTKRVIQ YFASIAAVGG GKKDTSKGTL EDQIIQANPA LEAFGNAKTL RNDNSSRFGK
FIRIHFGTSG KLSSADIETY LLEKSRVTFQ LKAERNYHIF YQILSNQKPE LLDMLLITNN
PYDYSYISQG EVTVASINDS EELMATDSAF DVLGFTPEEK MGVYKLTGAI MHYGNMKFKQ
KQREEQAEPD GTEAADKSAY LMGLNSADLI KGLCHPRVKV GNEYVTKGQS VDQVYYSLGA
LA
//
