ID   I6ZXV7_MELRP            Unreviewed;       634 AA.
AC   I6ZXV7;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Fe-only hydrogenase, subunit beta {ECO:0000313|EMBL:AFN73878.1};
GN   OrderedLocusNames=MROS_0635 {ECO:0000313|EMBL:AFN73878.1};
OS   Melioribacter roseus (strain JCM 17771 / P3M-2).
OC   Bacteria; Ignavibacteriota; Ignavibacteria; Ignavibacteriales;
OC   Melioribacteraceae; Melioribacter.
OX   NCBI_TaxID=1191523 {ECO:0000313|EMBL:AFN73878.1, ECO:0000313|Proteomes:UP000009011};
RN   [1] {ECO:0000313|EMBL:AFN73878.1, ECO:0000313|Proteomes:UP000009011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 17771 / P3M-2 {ECO:0000313|Proteomes:UP000009011};
RX   PubMed=23301019; DOI=10.1371/journal.pone.0053047;
RA   Kadnikov V.V., Mardanov A.V., Podosokorskaya O.A., Gavrilov S.N.,
RA   Kublanov I.V., Beletsky A.V., Bonch-Osmolovskaya E.A., Ravin N.V.;
RT   "Genomic analysis of Melioribacter roseus, facultatively anaerobic
RT   organotrophic bacterium representing a novel deep lineage within
RT   Bacteriodetes/Chlorobi group.";
RL   PLoS ONE 8:E53047-E53047(2013).
CC   -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00007523}.
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DR   EMBL; CP003557; AFN73878.1; -; Genomic_DNA.
DR   AlphaFoldDB; I6ZXV7; -.
DR   STRING; 1191523.MROS_0635; -.
DR   KEGG; mro:MROS_0635; -.
DR   PATRIC; fig|1191523.3.peg.663; -.
DR   eggNOG; COG1894; Bacteria.
DR   HOGENOM; CLU_014881_3_2_10; -.
DR   OrthoDB; 9761899at2; -.
DR   Proteomes; UP000009011; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd02980; TRX_Fd_family; 1.
DR   Gene3D; 3.10.20.600; -; 1.
DR   Gene3D; 3.30.70.20; -; 1.
DR   Gene3D; 6.10.250.1450; -; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR   Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR011538; Nuo51_FMN-bd.
DR   InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR   InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR   InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR43578:SF2; FE-HYDROGENASE, SUBUNIT BETA; 1.
DR   PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR   Pfam; PF01512; Complex1_51K; 1.
DR   Pfam; PF13187; Fer4_9; 1.
DR   Pfam; PF10589; NADH_4Fe-4S; 1.
DR   SMART; SM00928; NADH_4Fe-4S; 1.
DR   SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR   SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR   SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR   SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 2.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009011}.
FT   DOMAIN          576..605
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   DOMAIN          606..634
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   634 AA;  68690 MW;  E73291CBACDB57FF CRC64;
     MRKRFADLEE ISLSYKESGR LIKRRVTICA GTGCVANGSL EVYNEFLKQL ESSGIEHLIK
     IELKKESSDA VLVSSSGCQG FCQMGPLVTI EPDGIMYVQV GKDDVKNVVE RTLMGNEVIE
     ELLYTDLSSG KKCKGTEDIN FYKRQKRFVL GNCGRINPED IYEYIASDGY KAARRAILEM
     TDAQICQEIL RSGLRGRGGG GFPTGKKWEL TRQSVSDIKY VICNGDEGDP GAFMDRSIME
     GNPHSVIEGM MIAAKAIGAS KGYVYVRMEY PLAVKRLRIA VQQARELGLL GLNIFDSGFD
     FDIEIMEGAG AFVCGEETAL MASIEGNRGM PNPKPPFPAE SGLFGKPTLI NNVETLSSVP
     KIILNGPDYF SSIGTDNSPG TKTFALTGNV VNTGLIEVPF GTTLREIIFE IGGGVVNDNG
     EIDPDAFKAV QIGGPSGGCL VEEHLDLPLD FDSLGKVGAM VGSGGLVVMN KSTCMVQMAR
     FFMQFTQNES CGKCVLCREG TKQMLALLDD IMEGRATYET ISLLEELAGA VNKGSLCGLG
     KTAPNPVLST LHYFRDEYYA HVEQKRCPAK QCKALLTPVI IPELCKGCGV CLRKCPTGAI
     TGSKKEPHVI NEELCIKCMA CLEACRLNAV TIGG
//