ID I7CEA3_NATSJ Unreviewed; 467 AA.
AC I7CEA3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=CBS domain containing protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=NJ7G_0500 {ECO:0000313|EMBL:AFO55754.1};
OS Natrinema sp. (strain J7-2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=406552 {ECO:0000313|EMBL:AFO55754.1, ECO:0000313|Proteomes:UP000006507};
RN [1] {ECO:0000313|EMBL:AFO55754.1, ECO:0000313|Proteomes:UP000006507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J7-2 {ECO:0000313|EMBL:AFO55754.1,
RC ECO:0000313|Proteomes:UP000006507};
RX PubMed=22911826; DOI=10.1371/journal.pone.0041621;
RA Feng J., Liu B., Zhang Z., Ren Y., Li Y., Gan F., Huang Y., Chen X.,
RA Shen P., Wang L., Tang B., Tang X.F.;
RT "The complete genome sequence of Natrinema sp. J7-2, a haloarchaeon capable
RT of growth on synthetic media without amino acid supplements.";
RL PLoS ONE 7:E41621-E41621(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003412; AFO55754.1; -; Genomic_DNA.
DR RefSeq; WP_008456080.1; NC_018224.1.
DR AlphaFoldDB; I7CEA3; -.
DR STRING; 406552.NJ7G_0500; -.
DR GeneID; 13350342; -.
DR KEGG; nat:NJ7G_0500; -.
DR PATRIC; fig|406552.5.peg.438; -.
DR eggNOG; arCOG00626; Archaea.
DR HOGENOM; CLU_015237_4_1_2; -.
DR OrthoDB; 9671at2157; -.
DR Proteomes; UP000006507; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF17; UPF0053 INNER MEMBRANE PROTEIN YFJD; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..214
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 233..294
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 301..357
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 444..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 467 AA; 51504 MW; 768FD84346064BC6 CRC64;
MALSPLFAVP LAAYEVPVVG VGFDQSTVTV LGVVAIAALI GLSAFFSSSE IAMFNLPKHR
LERMIEDDIP GASLVKGLKD DPHRLLVTIL VGNNVVNIAM SSIATAILSI HFGGLAGVLL
ATFGITALVL LFGESVPKSY AVENTEAWSI RIARPLKATE YLLFPLIVLF DYLTRQINKL
IGSTGPIESP YVTRDEIQEM IESGEREGVL EEEEHEMLTR IFRFNNTIVK EVMTPRLDMT
AVPKDAAIDE AIETCIQSGH ARIPVYEGSL DNVQGVVHIR DLVRDLNYGE ADDGELELAD
LIQPTLHVPE SKNVDELLTE MRENRMHMAI VIDEFGTTEG LVTMEDMIEE IIGEILEGGE
EQPIEEIDDD TVLVRGEVNI EDVNEALDID LPEGQEFETI AGFIFNRAGR LVEEGEEITY
DGVRITVEDV ENTRIMMARL TKLEAAEGST EEPDSEPARV EPDENDE
//
