ID I7CS25_NATSJ Unreviewed; 415 AA.
AC I7CS25;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Cobalamin synthesis protein P47K {ECO:0000313|EMBL:AFO56898.1};
GN OrderedLocusNames=NJ7G_1654 {ECO:0000313|EMBL:AFO56898.1};
OS Natrinema sp. (strain J7-2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=406552 {ECO:0000313|EMBL:AFO56898.1, ECO:0000313|Proteomes:UP000006507};
RN [1] {ECO:0000313|EMBL:AFO56898.1, ECO:0000313|Proteomes:UP000006507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J7-2 {ECO:0000313|EMBL:AFO56898.1,
RC ECO:0000313|Proteomes:UP000006507};
RX PubMed=22911826; DOI=10.1371/journal.pone.0041621;
RA Feng J., Liu B., Zhang Z., Ren Y., Li Y., Gan F., Huang Y., Chen X.,
RA Shen P., Wang L., Tang B., Tang X.F.;
RT "The complete genome sequence of Natrinema sp. J7-2, a haloarchaeon capable
RT of growth on synthetic media without amino acid supplements.";
RL PLoS ONE 7:E41621-E41621(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP003412; AFO56898.1; -; Genomic_DNA.
DR RefSeq; WP_014863808.1; NC_018224.1.
DR AlphaFoldDB; I7CS25; -.
DR STRING; 406552.NJ7G_1654; -.
DR GeneID; 13352143; -.
DR KEGG; nat:NJ7G_1654; -.
DR PATRIC; fig|406552.5.peg.1473; -.
DR eggNOG; arCOG01233; Archaea.
DR HOGENOM; CLU_017452_2_0_2; -.
DR OrthoDB; 359387at2157; -.
DR Proteomes; UP000006507; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 275..387
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 239..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 45232 MW; DEA44B5739B663AB CRC64;
METDTDGAIP VTILSGSLGA GKTTLLNHLL SSADRTLAVL VNDMGDVNVD AELVAEGSEL
EIDDGVTELS NGCICCELQD DLETAVGRLA RDRSFDHLVV ESSGISEPAP VARLFTTESR
VAALYDVDTL VTVLDTPAFL DAFADEERPK RRGDEGDRPL SDLLVEQVEV SNLVLLNKAD
LCSDADLAAA EDLVSALQPE AETIPTVFSA VDPDRLLGAD LFGSGRVTDR PGWQRALEAA
DEHDHNESEH GAHDGQRAET GERHDHHHPD DVYGVSSFVY RSRRPFHPER FASVLRTLPR
SIVRSKGTVW LAGTEMRLSI AQAGPSVRAT AQGPWIASLP EVERDMYRSN RPDLEWHDEY
GDRRTELVVI GTDYDEGALR AALEDALVTD EEWATAFDGG PFPTTQGVET VIREP
//
