ID I7GE45_MACFA Unreviewed; 452 AA.
AC I7GE45;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Macaca fascicularis brain cDNA clone: QmoA-10959, similar to human upstream binding transcription factor, RNA polymerase I(UBTF), mRNA, RefSeq: NM_014233.1 {ECO:0000313|EMBL:BAE90957.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|EMBL:BAE90957.1};
RN [1] {ECO:0000313|EMBL:BAE90957.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17194215; DOI=10.1371/journal.pbio.0050013;
RA Wang H.-Y., Chien H.-C., Osada N., Hashimoto K., Sugano S., Gojobori T.,
RA Chou C.-K., Tsai S.-F., Wu C.-I., Shen C.-K.J.;
RT "Rate of evolution in brain-expressed genes in humans and other primates.";
RL PLoS Biol. 5:e13-e13(2007).
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DR EMBL; AB173895; BAE90957.1; -; mRNA.
DR AlphaFoldDB; I7GE45; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22001; HMG-box_UBF1_rpt4; 1.
DR CDD; cd22002; HMG-box_UBF1_rpt5; 1.
DR CDD; cd22003; HMG-box_UBF1_rpt6-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 4.
DR InterPro; IPR029215; HMG_box_5.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR46318; UPSTREAM BINDING TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF09011; HMG_box_2; 1.
DR Pfam; PF14887; HMG_box_5; 1.
DR SMART; SM00398; HMG; 4.
DR SUPFAM; SSF47095; HMG-box; 4.
DR PROSITE; PS50118; HMG_BOX_2; 3.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 95..163
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 170..237
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 256..322
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 95..163
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 170..237
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 256..322
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 62..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..434
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 452 AA; 52231 MW; F70F905568CADFFC CRC64;
MANMKDVPST ERMVLCSQQW KLLSQKEKDA YHKKCDQKKK DYEVELLRFL ESLPEEEQQR
VLGEEKMLNI NKKQATSPAS KKPAQEGGKG GSEKPKRPVS AMFIFSEEKR RQLQEERPEL
SESELTRLLA RMWNDLSEKK KAKYKAREAA LKAQSERKPG GEREERGKLP ESPKRAEEIW
QQSVIGDYLA RFKNDRVKAL KAMEMTWNNM EKKEKLMWIK KAAEDQKRYE RELSEMRAPP
AATNSSKKMK FQGEPKKPPM NGYQKFSQEL LSNGELNHLP LKERMVEIGS RWQRISQSQK
EHYKKLAEEQ QKQYKVHLDL WVKSLSPQDR AAYKEYISNK RKSMTKLRGP NPKSSRTTLQ
SKSESEEDDE EDEDDEDEDE EEEDDENGDS SEDGGDSSES SSEDESEDGD ENEEDDEDED
DDEDDDEDED NESEGSSSSS SSSGDSSDSD SN
//
