ID I7GK96_MACFA Unreviewed; 271 AA.
AC I7GK96; A0A2K5WXR4;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Signal recognition particle receptor subunit beta {ECO:0000256|ARBA:ARBA00020256};
GN Name=SRPRB {ECO:0000313|Ensembl:ENSMFAP00000041905.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|EMBL:BAE88385.1};
RN [1] {ECO:0000313|EMBL:BAE88385.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17194215; DOI=10.1371/journal.pbio.0050013;
RA Wang H.-Y., Chien H.-C., Osada N., Hashimoto K., Sugano S., Gojobori T.,
RA Chou C.-K., Tsai S.-F., Wu C.-I., Shen C.-K.J.;
RT "Rate of evolution in brain-expressed genes in humans and other primates.";
RL PLoS Biol. 5:e13-e13(2007).
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000041905.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSMFAP00000041905.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004389}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the SRP receptor beta subunit family.
CC {ECO:0000256|ARBA:ARBA00005619}.
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DR EMBL; AB171072; BAE88135.1; -; mRNA.
DR EMBL; AB171322; BAE88385.1; -; mRNA.
DR RefSeq; XP_005545852.1; XM_005545795.2.
DR RefSeq; XP_015300583.1; XM_015445097.1.
DR SMR; I7GK96; -.
DR STRING; 9541.ENSMFAP00000041898; -.
DR Ensembl; ENSMFAT00000016183.2; ENSMFAP00000041905.2; ENSMFAG00000039758.2.
DR GeneID; 101865228; -.
DR KEGG; mcf:101865228; -.
DR CTD; 58477; -.
DR VEuPathDB; HostDB:ENSMFAG00000039758; -.
DR GeneTree; ENSGT00940000154388; -.
DR OMA; DWEGGEV; -.
DR OrthoDB; 5393958at2759; -.
DR Proteomes; UP000233100; Chromosome 2.
DR Bgee; ENSMFAG00000039758; Expressed in pituitary gland and 13 other cell types or tissues.
DR GO; GO:0005881; C:cytoplasmic microtubule; IEA:Ensembl.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd04105; SR_beta; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR019009; SRP_receptor_beta_su.
DR PANTHER; PTHR11711; ADP RIBOSYLATION FACTOR-RELATED; 1.
DR PANTHER; PTHR11711:SF451; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT BETA; 1.
DR Pfam; PF09439; SRPRB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
PE 2: Evidence at transcript level;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000313|EMBL:BAE88385.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 271 AA; 29644 MW; F33BCA18E0FDFF72 CRC64;
MASADLRRVA DGGGAGGTFQ PYLDSLRQEL QQTDPTLLSV VVAVLAVLLT LVFWKLIRSR
RSSQRAVLLV GLCDSGKTLL FVRLLTGLYR DTQTSITDSS AVYRVNNNRG NSLTLIDLPG
HESLRLQFLE RFKSSARAIV FVVDSAAFQR EVKDVAEFLY QVLIDSMGLK NTPSFLIACN
KQDIAMAKSA KLIQQQLEKE LNTLRVTRSA APSTLDSSST APAQLGKKGK EFEFSQLALK
VEFLECSAKG GRGDAGSADI QDLEKWLAKI A
//
