ID I7GZJ0_9HELI Unreviewed; 682 AA.
AC I7GZJ0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:BAM33131.1};
GN ORFNames=HCBAA847_1913 {ECO:0000313|EMBL:BAM33131.1}, HCCG_00316
GN {ECO:0000313|EMBL:EFR45770.1};
OS Helicobacter cinaedi CCUG 18818 = ATCC BAA-847.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=537971 {ECO:0000313|EMBL:BAM33131.1, ECO:0000313|Proteomes:UP000006036};
RN [1] {ECO:0000313|EMBL:EFR45770.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCUG 18818 {ECO:0000313|EMBL:EFR45770.1};
RG The Broad Institute Genome Sequencing Platform;
RA Fox J.G., Shen Z., Charoenlap N., Schauer D.B., Ward D., Mehta T.,
RA Young S., Jaffe D., Gnerre S., Berlin A., Heiman D., Hepburn T., Shea T.,
RA Sykes S., Alvarado L., Kodira C., Borodovsky M., Lander E., Galagan J.,
RA Nusbaum C., Birren B.;
RT "Annotation of Helicobacter cinaedi strain CCUG 18818.";
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAM33131.1, ECO:0000313|Proteomes:UP000006036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-847 {ECO:0000313|EMBL:BAM33131.1,
RC ECO:0000313|Proteomes:UP000006036};
RX PubMed=23012276; DOI=10.1128/JB.01347-12;
RA Miyoshi-Akiyama T., Takeshita N., Ohmagari N., Kirikae T.;
RT "Complete Genome Sequence of Helicobacter cinaedi Type Strain ATCC
RT BAA-847.";
RL J. Bacteriol. 194:5692-5692(2012).
RN [3] {ECO:0000313|EMBL:BAM33131.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC BAA-847 {ECO:0000313|EMBL:BAM33131.1};
RA Akiyama T., Takeshita N., Ohmagari N., Kirikae T.;
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Proteomes:UP000005755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 18818 {ECO:0000313|Proteomes:UP000005755};
RX PubMed=25212613;
RA Shen Z., Sheh A., Young S.K., Abouelliel A., Ward D.V., Earl A.M.,
RA Fox J.G.;
RT "Draft genome sequences of six enterohepatic helicobacter species isolated
RT from humans and one from rhesus macaques.";
RL Genome Announc. 2:e00857-e00814(2014).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; AP012492; BAM33131.1; -; Genomic_DNA.
DR EMBL; DS990391; EFR45770.1; -; Genomic_DNA.
DR RefSeq; WP_002955593.1; NZ_DS990391.1.
DR AlphaFoldDB; I7GZJ0; -.
DR KEGG; hcb:HCBAA847_1913; -.
DR PATRIC; fig|1206745.3.peg.2005; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_399432_0_0_7; -.
DR OrthoDB; 1530at2; -.
DR Proteomes; UP000005755; Unassembled WGS sequence.
DR Proteomes; UP000006036; Chromosome 1.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:BAM33131.1};
KW Cilium {ECO:0000313|EMBL:BAM33131.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:BAM33131.1};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 18..109
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 432..666
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 682 AA; 74408 MW; 48AACBF93143BD80 CRC64;
MALGSLSSLG LGSKVLNHDV IDKLRKADES THIDPIDKKI EQNVEKQTEL VTITSTLRDL
KSSVSKLADY STYLGRSSNI IGDALKATIS TGVPTQDIKI DIDSVATSDI NEIGSKYESR
ESAFSQKDST LKFHYKGQDY KIEIKAGMEL AEVAQLITDT TKGEVMGIVM KTGGSNPYQL
MINSKDTGES SRVYFGSTAT GSVIPSGAFE LNDGDFNITL KDKKGIDKTL SIKLPKTATE
SKAQDNAQAL KEAVIATIKD NADFEGLLDN DLNIGIGGAN SDMLTINDRR GYGIKVEGAK
AQALGFGEDN KSTQKEDLMV ATKSVGAGLL TGTINIGSVP LDLSTLTNKK NTAKQNAQAI
ADAINNIAGI YGSVNDEGKL VINSDTGEVN IYANNDAESK KALEDLGLKS GTTMDYAKTQ
EDLFKIRKVQ TAEDAKFSYN GISMRRPTNN IDDIVSGVNI ELLTTTEPGK PAVISITRND
EEIIESVKSF VETYNELSLK LDEVTRYDED SKIAGIFNGN SDIRMIRPTL TRIFSTNIPT
ETEIKSLVKY GLALDEKGKM SLDTSKLSMA LSTDPEGTQE FFYGSVKSTE FKEVQTDGVF
KKFDQELDKL LNGGNARLKL LEESLTKDDK KLREDRKKAV EQLNIRYDIM AQRFAAYDSQ
ISKTNNAFSS VQLMIDQSVA KK
//
