ID I7JW48_9CORY Unreviewed; 397 AA.
AC I7JW48;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Thiamine pyrophosphokinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN46_0896 {ECO:0000313|EMBL:CCI83626.1}, HMPREF9719_00588
GN {ECO:0000313|EMBL:EJZ82363.1};
OS Corynebacterium otitidis ATCC 51513.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=883169 {ECO:0000313|EMBL:CCI83626.1, ECO:0000313|Proteomes:UP000011016};
RN [1] {ECO:0000313|EMBL:CCI83626.1, ECO:0000313|Proteomes:UP000011016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51513 {ECO:0000313|EMBL:CCI83626.1,
RC ECO:0000313|Proteomes:UP000011016};
RX PubMed=23045487; DOI=10.1128/JB.01412-12;
RA Brinkrolf K., Schneider J., Knecht M., Ruckert C., Tauch A.;
RT "Draft Genome Sequence of Turicella otitidis ATCC 51513, Isolated from
RT Middle Ear Fluid from a Child with Otitis Media.";
RL J. Bacteriol. 194:5968-5969(2012).
RN [2] {ECO:0000313|EMBL:EJZ82363.1, ECO:0000313|Proteomes:UP000006078}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51513 {ECO:0000313|EMBL:EJZ82363.1,
RC ECO:0000313|Proteomes:UP000006078};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Huys G., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Turicella otitidis ATCC 51513.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI83626.1}.
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DR EMBL; CAJZ01000121; CCI83626.1; -; Genomic_DNA.
DR EMBL; AHAE01000032; EJZ82363.1; -; Genomic_DNA.
DR RefSeq; WP_004600478.1; NZ_JH815193.1.
DR AlphaFoldDB; I7JW48; -.
DR STRING; 29321.AAV33_05085; -.
DR PATRIC; fig|883169.3.peg.559; -.
DR eggNOG; COG4825; Bacteria.
DR HOGENOM; CLU_046690_0_0_11; -.
DR OrthoDB; 5169996at2; -.
DR Proteomes; UP000006078; Unassembled WGS sequence.
DR Proteomes; UP000011016; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004788; F:thiamine diphosphokinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:InterPro.
DR InterPro; IPR047795; Put_SteA-like.
DR InterPro; IPR036759; TPK_catalytic_sf.
DR NCBIfam; NF040608; division_SteA; 1.
DR SUPFAM; SSF63999; Thiamin pyrophosphokinase, catalytic domain; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006078};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 358..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 397 AA; 41221 MW; 83B1FB34CFC06CEC CRC64;
MARMSLFSRK EELPGLSAPI RDLSRATRAS KAVQKVAAGD IVVIAEPNIS RGTAQLLVDL
EPAAVVNTAQ FSTGSVPLFG PQMLLDAGIT LVEDAGVDVL EHLRDGKTAR LTDSGELFHG
ETLLGSGRVL TQAGVEFDFS EAERNLVERV EAYFGNTVEF LRSEAPLLID GLGVPETGLD
ATGEAALVIA PGPEQGRVLK DLRGFIKARS PMIVAIDEAA DLVVEQGYTP DVALGDPTRI
QAATLRAARR VVLPAAPDGH AAGLERIQDL GVGAMTFPAA TESTTDLGLL LAHFHGADLI
VNASEPLTLD AIIGERAGLG EPLQSPAALL TRLRVADKLV GVAAAAEIGT RREGAGGAWL
LAILGVLAAI VSVVLVAGFG GGDGFAENLE QTFGNLV
//
