ID I7LA90_9LACO Unreviewed; 316 AA.
AC I7LA90;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:CCI82059.1};
GN ORFNames=BN55_01785 {ECO:0000313|EMBL:CCI82059.1};
OS Lactobacillus hominis DSM 23910 = CRBIP 24.179.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423758 {ECO:0000313|EMBL:CCI82059.1, ECO:0000313|Proteomes:UP000009320};
RN [1] {ECO:0000313|EMBL:CCI82059.1, ECO:0000313|Proteomes:UP000009320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRBIP 24.179T {ECO:0000313|Proteomes:UP000009320};
RA Cousin S., Ma L., Bizet C., Loux V., Bouchier C., Clermont D., Creno S.;
RT "Draft Genome Sequence of Lactobacillus hominis Strain CRBIP 24.179T,
RT isolated from human intestine.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI82059.1}.
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DR EMBL; CAKE01000013; CCI82059.1; -; Genomic_DNA.
DR RefSeq; WP_008471030.1; NZ_CAKE01000013.1.
DR AlphaFoldDB; I7LA90; -.
DR STRING; 1423758.FC41_GL000683; -.
DR GeneID; 82847282; -.
DR PATRIC; fig|1423758.3.peg.689; -.
DR eggNOG; COG1609; Bacteria.
DR OrthoDB; 9796186at2; -.
DR Proteomes; UP000009320; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF146; LMO2128 PROTEIN; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..56
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 316 AA; 35591 MW; 68FC323328F406D8 CRC64;
MPTLSDVAKE ANVSKMTVSR VINHPNQVTP ELRKIVLEAM HRLNYHPNSA ASALASNRTN
VVKFVILEDI DTTEPYYMNL LFGIAQGLQK QQFALQLVRD AADVDKGNCD GYIITGARAT
DSDWLDKLKK PFVLFGENRY GYDFIDTDNK LGDQLATQYA IDRNYQSIIF MGIDEKEPFE
YSREAGYINT LQKYKKIPRI FRVANHSRKA QDFITNNWKK FAPDTCFICA SDRIAVGVVR
AIQEKGGKIP KDFGVIGFDG VFLDQVSNPK LTTIKQPIFE LGQSLATMIL QKVAQNGAAQ
GELLMPPELI KRESTR
//
