ID I7MH07_TETTS Unreviewed; 495 AA.
AC I7MH07;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Flavin-binding monooxygenase-like protein {ECO:0000313|EMBL:EAR85652.1};
GN ORFNames=TTHERM_00420600 {ECO:0000313|EMBL:EAR85652.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR85652.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183}.
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DR EMBL; GG662536; EAR85652.1; -; Genomic_DNA.
DR RefSeq; XP_001033315.1; XM_001033315.3.
DR AlphaFoldDB; I7MH07; -.
DR STRING; 312017.I7MH07; -.
DR EnsemblProtists; EAR85652; EAR85652; TTHERM_00420600.
DR GeneID; 7831454; -.
DR KEGG; tet:TTHERM_00420600; -.
DR eggNOG; KOG1399; Eukaryota.
DR HOGENOM; CLU_529478_0_0_1; -.
DR InParanoid; I7MH07; -.
DR OrthoDB; 2453855at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR PANTHER; PTHR23023:SF266; FLAVIN-CONTAINING MONOOXYGENASE; 1.
DR Pfam; PF00743; FMO-like; 2.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033, ECO:0000313|EMBL:EAR85652.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
SQ SEQUENCE 495 AA; 57849 MW; 4E2AEC09984B6DD6 CRC64;
MSAFNQLRED QYKNNYSQKS VIVVGAGPLG ILSVRYLSQE TDLNTICFEA KNNIGGMWYL
DDYDRLDSEI NTSKNAFIRD NGYVQSSLYE NLRLNSVKMK TMYKGYPIPK EFHEYMKQDE
FLQYMRGFAD NYGLKNYISF ETYVNYVRLV GNMTQSEKEQ IPINLTKKFL VEVVSYNNYE
KDVRHFQADY VICCSGHYSK PNIIKIPNQQ IFEGKIDHTH HFRERDGKQL ANKNLVIIGQ
NTSCQDIFSL LLFESEITPK KITVIGRNSV QHLKNATSLQ EVIKKGLIEF IQDECQEFNS
KNSLLLKSGK IIENIDSILL ATGYQFCFHY LNKFNHIDNC IEYYENNRSI GPLYNKIISI
NEPNLIFLGS INGSSQQHYE RQAIYSTHYI LGKLTLPTKE EMMQDFEDEL KKNGGKKGYL
GILKLPNFTS NHDQYVKKLY RDMKGIEFDD ELQQTWLLYA KLYEKHSNAG NYYEMKFEDL
SQMPTRDYVP KLGLF
//
