ID I7MIX3_TETTS Unreviewed; 286 AA.
AC I7MIX3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Poly polymerase and DNA-ligase Zn-finger region family protein, putative {ECO:0000313|EMBL:EAS04828.1};
GN ORFNames=TTHERM_00467770 {ECO:0000313|EMBL:EAS04828.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS04828.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662441; EAS04828.1; -; Genomic_DNA.
DR RefSeq; XP_001025073.1; XM_001025073.3.
DR AlphaFoldDB; I7MIX3; -.
DR STRING; 312017.I7MIX3; -.
DR EnsemblProtists; EAS04828; EAS04828; TTHERM_00467770.
DR GeneID; 7830472; -.
DR KEGG; tet:TTHERM_00467770; -.
DR HOGENOM; CLU_1006312_0_0_1; -.
DR InParanoid; I7MIX3; -.
DR OrthoDB; 202835at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.90.640.80; -; 1.
DR Gene3D; 3.30.1740.10; Zinc finger, PARP-type; 1.
DR InterPro; IPR012982; PARP1-like_PADR1_Zn_ribbon.
DR InterPro; IPR001510; Znf_PARP.
DR InterPro; IPR036957; Znf_PARP_sf.
DR Pfam; PF08063; PADR1_Zn_ribbon; 1.
DR SMART; SM01335; PADR1; 1.
DR SMART; SM01336; zf-PARP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS52007; PADR1; 1.
DR PROSITE; PS50064; ZF_PARP_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 19..68
FT /note="PARP-type"
FT /evidence="ECO:0000259|PROSITE:PS50064"
FT REGION 83..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 286 AA; 32658 MW; D4CC4C04A9368892 CRC64;
MNFYDYDSNT PEYKFYEDLY LEVSVSNKAK CRSCGKTIDK DVLRWCSSER DRAEPIYVSK
RYYHQKCLPP VAGHPIVDYN PKTQTGKLKN MNVNPSKQTE KDLFNNAVDE YVKYRNNYDK
KSKKQDKNWD PDNSDSDSGE EVVKKAKKAT KVNKSEKKTN KRSKADDSDE DIDAEVSLAG
YTDGQRQKYL KKLEELKSKT VAQLKAILKA NNQTQTGTKE VLLEKVADGY TLGAIPQCTK
CGGGKLRFNK STGEYTCPGF MEDTDKVDCD AVFSIDQVVR FDWVEP
//
