ID I7MKZ3_TETTS Unreviewed; 754 AA.
AC I7MKZ3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=FYVE zinc finger protein {ECO:0000313|EMBL:EAS00662.2};
GN ORFNames=TTHERM_00412130 {ECO:0000313|EMBL:EAS00662.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS00662.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662612; EAS00662.2; -; Genomic_DNA.
DR RefSeq; XP_001020907.2; XM_001020907.2.
DR AlphaFoldDB; I7MKZ3; -.
DR GeneID; 7825763; -.
DR KEGG; tet:TTHERM_00412130; -.
DR InParanoid; I7MKZ3; -.
DR OrthoDB; 354414at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF01363; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 20..79
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT COILED 430..500
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 754 AA; 88396 MW; 88E4427F51FBF685 CRC64;
MEVANRTIYQ ISLQDQLFKS NQCEICSYSF GLFKKSYYCK RCYRTICQPC GQNRCIIPGS
LKQDKKPRRI CVKCAEEQKV NLGTISKCQL VFGEDSQIGL NWLRYLNTNK QEVDEDFQEQ
CQKSNKELQS NKDLQKKVQQ AQLALEKGFI APNAFNFSIF EIVYELQIDY KQSKEKVLGI
LIPFFNIYKK LNVSVELLQL SYFFLLLSSQ SLAFKFLKSY FSIFPSYVME SEKVIDVLSQ
KINSQFQNEP FCKNNKNFDL NFLAQKYHKY ISSFFVNFLR FETQITLIDS IFISKSVRFL
FSITVSQYFW QAIDNQFFFQ RTNFILIINA LSKQESQIHL QLKFNRLEQT IFKVFQDFLT
QKMLHNRFDR YLLLISSNTI FQNLPRSLSK QYTQDLETLN TQNNEEGDYS DSEEIVQIAG
SQFKKKRISQ SYYEQENQEL KKKLQEKNDQ IKGLQEKLFS LSVKPNQQEQ VLIKKMQSDI
NLLQKKIKDQ QKFIEELTQK IIKQAKEKED SSQVDKARQM IQVELKEMCN QIKAQVNEEI
QSQLKANITE TFQNLTPNKS IENVDNIQYE NYQSSNFLST ALNSNINNKQ NHKSFEIQTG
NKQKNESFFS TIYNNHSRQN SQFADVQFMN NLLGEINQQQ LNFQVTNNQI QSGKQGHFTV
QSVDNNANLQ KTNEKVAKKS MSVCDDDKEI ISSSLDISRN TKKSNTSSES IREDYLAFDQ
SIIERLDKLQ GLLLKDQKII SQLFFQESTK LSSQ
//
