ID I8R2J4_LACPE Unreviewed; 621 AA.
AC I8R2J4;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Sorbitol/glucitol operon transcription regulator {ECO:0000313|EMBL:EIW12593.1};
GN Name=srlR2 {ECO:0000313|EMBL:EIW12593.1};
GN ORFNames=KCA1_2992 {ECO:0000313|EMBL:EIW12593.1};
OS Lactiplantibacillus pentosus KCA1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=1136177 {ECO:0000313|EMBL:EIW12593.1};
RN [1] {ECO:0000313|EMBL:EIW12593.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCA1 {ECO:0000313|EMBL:EIW12593.1};
RX PubMed=23527145;
RA Anukam K.C., Macklaim J.M., Gloor G.B., Reid G., Boekhorst J., Renckens B.,
RA van Hijum S.A., Siezen R.J.;
RT "Genome Sequence of Lactobacillus pentosus KCA1: Vaginal Isolate from a
RT Healthy Premenopausal Woman.";
RL PLoS ONE 8:E59239-E59239(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIW12593.1}.
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DR EMBL; AKAO01000083; EIW12593.1; -; Genomic_DNA.
DR RefSeq; WP_003640199.1; NZ_CM001538.1.
DR AlphaFoldDB; I8R2J4; -.
DR PATRIC; fig|1136177.4.peg.3055; -.
DR eggNOG; COG1762; Bacteria.
DR eggNOG; COG3711; Bacteria.
DR HOGENOM; CLU_013442_5_3_9; -.
DR Proteomes; UP000005826; Chromosome.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.1790.10; PRD domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30185; CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR; 1.
DR PANTHER; PTHR30185:SF18; TRANSCRIPTIONAL REGULATOR MTLR; 1.
DR Pfam; PF08279; HTH_11; 2.
DR Pfam; PF00874; PRD; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51372; PRD_2; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 274..380
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 473..621
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
SQ SEQUENCE 621 AA; 71247 MW; 302FF79964C06B6B CRC64;
MDRQSFEILN FFINNDALTL RELQAHFSVS RVTITKNIRS INEYLAGIAK INVNQAKFYL
VINNYSAIAK LQTNFLKKDL DFNDPSKRQA TILKELLQQK TDYIILDDLA ESLAVSRGTI
NKDLKTLKQH LAFYHVDIET KTNRGIHLSV QHDYVYAVIT RTLVGKYYEL EATWDNATDA
KLINLIQQID HSSDTVTRVK RNVAVINWLR KYDIRINDDI QNYHSLLSDE TTNALRNLIT
EIVGSSLSTG EWQFISYPLN IKKVPKDDSH LVRAALDDVA DLMQLVFPIL KQKLDVNLDF
ERLLVELQYH LLFLINRAIF DVKSEGFISV DMLSKYPVST ELAQITLSTI AAKLNIRIRS
QEVGYLTVYF QMELEEYMAA PIIHRVALVK PINTSMKKFI SEKLKEMLDD DLQIDVFNSI
KELEQSPEKY LLIFSNSFLT GNERINHAPI IRLNSIFNQG ALRERLQISL VDEAINQGQC
RFGVTKLDSQ ETYIDGVKKL INHEVEDGQL TQEFMQDWIN REQQSSSIFG DGVALPHVID
KSGLNRILVT VGLFEKPVVF DNQKVNVVFL VAIPYKLDAT LSKILAQVYD LIRSITTNSN
IFNNLKNYDS NRGLNQLMEA I
//
