ID I8U0P7_ASPO3 Unreviewed; 1013 AA.
AC I8U0P7;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=von Willebrand and RING finger domain protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=Ao3042_03192 {ECO:0000313|EMBL:EIT80355.1};
OS Aspergillus oryzae (strain 3.042) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=1160506 {ECO:0000313|EMBL:EIT80355.1, ECO:0000313|Proteomes:UP000002812};
RN [1] {ECO:0000313|EMBL:EIT80355.1, ECO:0000313|Proteomes:UP000002812}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3.042 {ECO:0000313|EMBL:EIT80355.1,
RC ECO:0000313|Proteomes:UP000002812};
RX PubMed=22933657; DOI=10.1128/EC.00160-12;
RA Zhao G., Yao Y., Qi W., Wang C., Hou L., Zeng B., Cao X.;
RT "Draft genome sequence of Aspergillus oryzae strain 3.042.";
RL Eukaryot. Cell 11:1178-1178(2012).
RN [2] {ECO:0000313|Proteomes:UP000002812}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3.042 {ECO:0000313|Proteomes:UP000002812};
RA Zhao G., Hou L., Wang C., Cao X.;
RT "Comparative genomic analyses of Aspergillus oryzae 3.042 and A. oryzae
RT RIB40 for soy-sauce fermentation.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIT80355.1}.
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DR EMBL; AKHY01000116; EIT80355.1; -; Genomic_DNA.
DR AlphaFoldDB; I8U0P7; -.
DR HOGENOM; CLU_006368_0_0_1; -.
DR Proteomes; UP000002812; Unassembled WGS sequence.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 23..69
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 495..668
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 97..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..164
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 887..921
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1013 AA; 111887 MW; B413E6C04EFF2169 CRC64;
MAGLTEVDRT RSRRDRTFVG SECAVCEEPL EHTLRGERVL QFSCAHVAHE ACFYEFIREF
EGQYCPTCDA PLGLDTSRGG NVLDIEKLSN MVRSVTSDAA TQRSGMTGAT TPWDQSTNVS
RGRLPSDAGS RPYNRDSRDI YSRRDSRDTG DPRERIERLT SGSRQHHSRN GSAAGSSGDY
NDTQHPSNGR RHDYDLQAME SELSPRSGPT KNPIPAPTMT IRSEFPTLNR SRQQQPLTCL
ITIEVPEGWR ADSDDLRHTS TGSPQPEDEP YSMMRFPAAQ EPRPSPYESQ ENLDEIAEEL
RTKVDNWHGL EFQRFGKLRL HGQMRVGKDR ESWQDLQCYL FAEMLICIKE KKVSDHRRQY
DDKPRHTRCT LKGSILIKKH LKHIDADPDE PVLTLSLSVS ELPCFYLSFQ NRNQLEIWRR
ALLDLHQLDS LSRGADYDLD NSGAEEEDYR NSQIKRQASL NSSYGAARSN NTAITDYTSV
AVESGPSPSL HIPLDIVVVI PVSSSMQGLK ITLLRDALKF LVQNLGPRDR MGLVTFGSSG
GGVPLVGMTT KSWGGWGKIL NSIRPVGQKS LRADVVEGAN VAMDLLMQRK LSNPISTILL
ISDSSTSDPD SVDFVVSRAE AAKVSIHSFG LGLTHKPDTM IELSTRTKGS YLYVKDWMML
RECVAGCLGA LQTTSHQNVK LKLRLPEGSP AKFVKISGAL HTTKRATGRD AEAALGDLRF
GDKRDILVQL VIQPDNSSQE NMPQDPWESL VSGLEALGGG SDGDEQRVLS VEEVPLIQAD
ITYGDLLRDG HLTHSPRPSL LAITMLPPNP KSRHSSRPMT PPIPPHPSIV QRRMELLTSD
MLTRALTLVS RGHHDRAQHL LIETRSILKG LGKGSLPPLP PGAVKPSSIS DSGSRGDTPT
STSPRSSTFG DSHSSAVSDS ATITPGAAVD AQTMQALDGD LKAALEWINH PAVFGRDSRK
AVLQGIGVIS SQRAYTFRSP SEAHWAQRVA GVRRLTERSK EWRETGDDAL TEE
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