ID I9LHW0_9FIRM Unreviewed; 358 AA.
AC I9LHW0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:EIW20109.1};
GN ORFNames=FB4_2541 {ECO:0000313|EMBL:EIW20109.1};
OS Pelosinus fermentans B4.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Pelosinus.
OX NCBI_TaxID=1149862 {ECO:0000313|EMBL:EIW20109.1, ECO:0000313|Proteomes:UP000004324};
RN [1] {ECO:0000313|EMBL:EIW20109.1, ECO:0000313|Proteomes:UP000004324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B4 {ECO:0000313|EMBL:EIW20109.1,
RC ECO:0000313|Proteomes:UP000004324};
RX PubMed=22933770; DOI=10.1128/JB.01174-12;
RA Brown S.D., Podar M., Klingeman D.M., Johnson C.M., Yang Z.K.,
RA Utturkar S.M., Land M.L., Mosher J.J., Hurt R.A.Jr., Phelps T.J.,
RA Palumbo A.V., Arkin A.P., Hazen T.C., Elias D.A.;
RT "Draft Genome Sequences for Two Metal-Reducing Pelosinus fermentans Strains
RT Isolated from a Cr(VI)-Contaminated Site and for Type Strain R7.";
RL J. Bacteriol. 194:5147-5148(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIW20109.1}.
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DR EMBL; AKVJ01000010; EIW20109.1; -; Genomic_DNA.
DR RefSeq; WP_007931590.1; NZ_AKVJ01000010.1.
DR AlphaFoldDB; I9LHW0; -.
DR PATRIC; fig|1149862.3.peg.828; -.
DR OrthoDB; 9809068at2; -.
DR Proteomes; UP000004324; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..271
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 358 AA; 38494 MW; BBC1C9EB43D2CDE2 CRC64;
MIWNRINHYK KWVILLIVAA ALGGGGAYYL KKNSTPVVAG TTAVIGRGDV IEAISATGTI
SAVNSVDISS RVTGLISELR VQENDMVKKG QVLVVLDDTT IKAQIAQYQA QMENYAVIYE
RSQKLAAIGA EPQQQLDTDR TNYLVAQSTY NSNASQVGYY VITAPIDGMV IGTPTPAGQT
VAQGISTPQV IMTIADMSKM QIKVLVDESD IGRVKMGQEV TFTVDSYTTQ TFAGKVTRIS
RSATTSSNVV YYPVYVDVDS TESLLYPTMT ARVTIKASES KNVLVAPLAA VKEDKGQKYV
QLMVNGKEQN VPVSIGLSDD EKVEIRSGLN EGDTILVPAT KARTAATTTQ NQGPPPPM
//
