ID I9PRZ0_9BACE Unreviewed; 604 AA.
AC I9PRZ0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Beta-galactosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1061_03144 {ECO:0000313|EMBL:EIY19158.1};
OS Bacteroides caccae CL03T12C61.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=997873 {ECO:0000313|EMBL:EIY19158.1, ECO:0000313|Proteomes:UP000002965};
RN [1] {ECO:0000313|EMBL:EIY19158.1, ECO:0000313|Proteomes:UP000002965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL03T12C61 {ECO:0000313|EMBL:EIY19158.1,
RC ECO:0000313|Proteomes:UP000002965};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides caccae CL03T12C61.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIY19158.1}.
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DR EMBL; AGXF01000014; EIY19158.1; -; Genomic_DNA.
DR AlphaFoldDB; I9PRZ0; -.
DR PATRIC; fig|997873.3.peg.3278; -.
DR HOGENOM; CLU_009935_3_1_10; -.
DR OrthoDB; 9801077at2; -.
DR Proteomes; UP000002965; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF2; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..604
FT /note="Beta-galactosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003723822"
FT DOMAIN 60..207
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 214..308
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 351..477
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 604 AA; 69618 MW; 3F3E456666903672 CRC64;
MIKQLFSIGI ALSLFSQMLW AQWTPVGDRI KTSWAEKIDV NNVLPEYPRP IMERSEWSNL
NGLWKYAVLP LGKSIPDSFE GDILVPFAVE SSLSGVGKTL GEDKELWYQR EFVIPSKWRG
KRILLHFGAV DWKTEVWVNN IKVGEHTGGF TPFTFDITQA LKNSENNLVV KVWDPTEKGT
QPRGKQVSNP HGIWYTPVSG IWQTVWLEPV SEHYITDIKT TPDIDLNKVK VKVETDDNRY
SDKFEVKVFE GGRLVAVGTS INGLPVEVSM PADAKLWSPD EPFLYQMEVS LFEGGKRVDC
VRSYMAMRKY SMKRDKKGIV RLQLNNKDLF QFGPLDQGWW PDGLYTAPTD EALCYDIKKT
KDLGFNMIRK HVKVEPARWY TYCDQMGVIV WQDMPNGDKT LEWQRKKYFD GTELARSPES
EATYRKEWKE IIDYLYSYPC IGTWVPFNEA WGQFKTSEIA EWTKQYDSTR LVNPASGGNH
YTCGDMLDLH NYPGPEMYLY DAQRATVLGE YGGIGLVLKN HLWEPNRNWG YIQFNTSTEA
TAEYLKYAEM LKEMIKQGFS AAVYTQTTDV EVEVNGLMTY DRKVIKLDEA TLKKINNEIC
KTLK
//
