ID I9Q4X9_HELPX Unreviewed; 713 AA.
AC I9Q4X9;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Hydantoin utilization protein A {ECO:0000313|EMBL:EJB29626.1};
DE EC=3.5.2.14 {ECO:0000313|EMBL:EJB29626.1};
GN Name=hyuA {ECO:0000313|EMBL:EJB29626.1};
GN ORFNames=HPNQ4200_0762 {ECO:0000313|EMBL:EJB29626.1};
OS Helicobacter pylori NQ4200.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992024 {ECO:0000313|EMBL:EJB29626.1, ECO:0000313|Proteomes:UP000003358};
RN [1] {ECO:0000313|EMBL:EJB29626.1, ECO:0000313|Proteomes:UP000003358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NQ4200 {ECO:0000313|EMBL:EJB29626.1,
RC ECO:0000313|Proteomes:UP000003358};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJB29626.1}.
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DR EMBL; AKNS01000005; EJB29626.1; -; Genomic_DNA.
DR RefSeq; WP_000650673.1; NZ_AKNS01000005.1.
DR AlphaFoldDB; I9Q4X9; -.
DR PATRIC; fig|992024.3.peg.737; -.
DR Proteomes; UP000003358; Unassembled WGS sequence.
DR GO; GO:0047423; F:N-methylhydantoinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EJB29626.1}.
FT DOMAIN 9..197
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 222..508
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 522..711
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
SQ SEQUENCE 713 AA; 78440 MW; ABD1B3356773CCEF CRC64;
MKDARVSVMG IDAGGTMTDT FFVKENGSFV VGKAQSNPED ESLAIYNSSQ DALSHWQSDV
SKVYPELVTC VYSGTAMLNR VVQRRGMEVG LICNKGFEQM HSMGRALQSY LGYALEERLH
INTHKYDDPL IPLKRIRGIT ERTDVKGQVV IPVRQEEVKV AVKELLEAGA KAIVICLLQS
HKNAESERIV RDIALKELEK LGKSIPVFAS VDYYPQRKES HRMNTTILEA YAAEPSRQTL
SKVSNRFKEH GAKFDLRVMA THGGTISWKA KELARTIVSG PIGGVIGSKL LGETLGYDNI
ACSDIGGTSF DMALIVKSNF NIASDPDMAR LVLSLPLVAM DSVGAGAGSF VRIDPHSQSV
KLGPDSAGYR VGTCWKDSGL DTVSVTDCHI VLGYLNPDNF LGGLIKLDVD RAKKHIKEQI
ADPLGISVED AAAGVIELLD LDLKEYLRSN ISAKGYSPSD FVCFSYGGAG PVHTYGYTEG
LGFKDVVVPA WAAGFSAFGC ACADFEYRYD KSVDIAIPQY SSDKSKTEAC KIIQDAWDEL
TLKVIEEFKI NGFSEKDVIL RPGYRMQYMG QLNDLEITSP VSKAASVADW EEIVKEYEKT
YARVYSESAC SPELGFSVTG VIMRGVVATQ KPVIPVEKEH GATPPKEAKI GVRKFYRHKK
WVDADVWQME KLLPGNEVIG PAIVESDATT FVIPKGFATR LDKHRLFHLK EIK
//
