ID I9QNB9_HELPX Unreviewed; 685 AA.
AC I9QNB9;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:EJB35961.1};
GN ORFNames=HPNQ4044_1005 {ECO:0000313|EMBL:EJB35961.1};
OS Helicobacter pylori NQ4044.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992028 {ECO:0000313|EMBL:EJB35961.1, ECO:0000313|Proteomes:UP000003026};
RN [1] {ECO:0000313|EMBL:EJB35961.1, ECO:0000313|Proteomes:UP000003026}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NQ4044 {ECO:0000313|EMBL:EJB35961.1,
RC ECO:0000313|Proteomes:UP000003026};
RA Blanchard T.G., Czinn S.J., McCracken C., Abolude K., Maroo A.,
RA Santana-Cruz I., Tallon L.J., Ficke F.W.F.;
RT "Genome sequence of Helicobacter pylori NQ4044.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJB35961.1}.
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DR EMBL; AKNW01000007; EJB35961.1; -; Genomic_DNA.
DR RefSeq; WP_001875037.1; NZ_AKNW01000007.1.
DR AlphaFoldDB; I9QNB9; -.
DR PATRIC; fig|992028.3.peg.981; -.
DR Proteomes; UP000003026; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:EJB35961.1};
KW Cilium {ECO:0000313|EMBL:EJB35961.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:EJB35961.1};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 19..108
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 433..668
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 685 AA; 74161 MW; 499CDC92D2515DC7 CRC64;
MAIGSLSSLG LGSKVLNYDV IDKLKDADEK ALIAPLDKKM EQNVEKQKAL VEIKTLLSAL
KGPVKTLSDY STYISRKSNV IGDALSASVG AGVPIQDIKV DVQNLAQGDI NELGAKFSSR
DDIFSQVDTT LKFYTQDKDY AVDIKAGMTL GDVAQSITDA TNGEVMGIVM KTGGNDPYQL
MVNTKNTGED NRVYFGSHLQ STLTNKNALS LGLDGAGKSE LSLNLKGADG SMHEVPIMLE
LPESASIKQK NAAIQKAMEQ ALENDPNFKD LIANGDISID TLHGGESLII NDRRGGNIEI
KGSKAKELGF SQTTTQESDL LKSARTTKEG KLEGVVSLNG QKLDLKALTK ESNTSEENTD
AIIQAINSKE GLNAFKNSEG KLVINSKTGM LTIKGEDALG KASLKDLGLS AGMVQSYEAS
QNTLFMSKNL QKASDSVFTY NGVSITRPTN EVNDVISGVN ITLEQTTEPN KPAIISVSRD
NQAIIDSLKE FVKAYNELIP KLDEDTRYDA DTKIAGIFNG VGDIRAIRSS LNNVFSYSVH
TDNGVESLMK YGLSLDDKGV MSLDEAKLSS ALNSNPKATQ DFFYGSDSKD MGGREIHQEG
IFSKFNQVIA NLIDGGNAKL KIYEDSLDRD AKSLTKDKEN AQELLKTRYN IMAERFAAYD
SQISKANQKF NSVQMMIDQA AAKKN
//
