ID   I9SCG4_HELPX            Unreviewed;       765 AA.
AC   I9SCG4;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Acetone carboxylase subunit alpha {ECO:0000313|EMBL:EJB54364.1};
DE            EC=6.4.1.6 {ECO:0000313|EMBL:EJB54364.1};
GN   Name=acxB {ECO:0000313|EMBL:EJB54364.1};
GN   ORFNames=HPHPH28_0815 {ECO:0000313|EMBL:EJB54364.1};
OS   Helicobacter pylori Hp H-28.
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=992041 {ECO:0000313|EMBL:EJB54364.1, ECO:0000313|Proteomes:UP000005158};
RN   [1] {ECO:0000313|EMBL:EJB54364.1, ECO:0000313|Proteomes:UP000005158}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hp H-28 {ECO:0000313|EMBL:EJB54364.1,
RC   ECO:0000313|Proteomes:UP000005158};
RA   Blanchard T.G., Czinn S.J., McCracken C., Abolude K., Maroo A.,
RA   Santana-Cruz I., Tallon L.J., Ficke F.W.F.;
RT   "Genome sequence of Helicobacter pylori Hp H-28.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJB54364.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AKOI01000011; EJB54364.1; -; Genomic_DNA.
DR   RefSeq; WP_001285061.1; NZ_AKOI01000011.1.
DR   AlphaFoldDB; I9SCG4; -.
DR   PATRIC; fig|992041.3.peg.787; -.
DR   Proteomes; UP000005158; Unassembled WGS sequence.
DR   GO; GO:0018710; F:acetone carboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:EJB54364.1}.
FT   DOMAIN          40..619
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   765 AA;  86532 MW;  73CB47BC4C850C82 CRC64;
     MANLLKNGKT LKQARDEILA RTEKTGHYNG LKKLEFKERD PIGYEKMFSK LRGGIVHARE
     TAKRIAASPI VEQEGELCFT LYNAVGDSVL TSTGIIIHVG TMGSAIKYMV ENNWEDNPGI
     NDKDIFTNND CAIGNVHPCD IMTLVPIFHD EKLIGWVGGV THVIDTGSVT PGSMSTGQVQ
     RFGDGYMITC RKTGANDESF KDWLHESQRS VRTPKYWILD ERTRIAGCHM IRDLVMEVIK
     EDGIDSYMRF IDEVIEEGRR GLISRIKSMT IPGKYRKVAF VDVPYAHKDI GVCSEFAKLD
     TIMHSPVEIT INKDATWKLD FDGASRWGWH SFNCNQVSFT SGIWVMMTQT LIPTSRINDG
     AYFATQFRLK KGTWMNPDDR RTGHAYAWHF LVSGWSALWR GLSQAYYSRG YLEEVNSGNA
     NTSNWLQGGG INQDGEIHAV NSFETSSCGT GACAIKDGLN HAAAIWNPEG DMGDVEIWEM
     AEPLLYLGRN VKANTGGYGK YRGGNGFETL RMVWGAHDWT MFFMGNGYMN SDWGMMGGYP
     AASGYRFEAH NTDLENRIKN NASLPLGGDF NPTDRDYEKH ISHASQVKRD KQCITTENCF
     DNYDLYLNYI KGGPGFGDPI ERDLNAILED LNSKQLLPEY AYKVYGAVVS QNKDGVWVGD
     EAKTKARRKE ILENRKARSI PVKQWMEQER NAILEKEASK QVKHMYATSF DLSPKFLNDF
     KTFWNLPKSW TMKEDELGVF TYGSKYRMDL SKLPDVRTVL LVDEK
//