ID I9SCN5_9BACE Unreviewed; 971 AA.
AC I9SCN5;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Fibronectin type-III domain-containing protein {ECO:0000259|PROSITE:PS50853};
GN ORFNames=HMPREF1068_00816 {ECO:0000313|EMBL:EIY53646.1};
OS Bacteroides nordii CL02T12C05.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=997884 {ECO:0000313|EMBL:EIY53646.1, ECO:0000313|Proteomes:UP000003089};
RN [1] {ECO:0000313|EMBL:EIY53646.1, ECO:0000313|Proteomes:UP000003089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL02T12C05 {ECO:0000313|EMBL:EIY53646.1,
RC ECO:0000313|Proteomes:UP000003089};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides nordii CL02T12C05.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC residues in alpha-D-galactosides, including galactose
CC oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC Evidence={ECO:0000256|ARBA:ARBA00001255};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing branched (1->3)-alpha-D-
CC galactosidic residues, producing free D-galactose.; EC=3.2.1.n1;
CC Evidence={ECO:0000256|ARBA:ARBA00001271};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIY53646.1}.
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DR EMBL; AGXS01000011; EIY53646.1; -; Genomic_DNA.
DR RefSeq; WP_007483740.1; NZ_JH724314.1.
DR AlphaFoldDB; I9SCN5; -.
DR STRING; 997884.HMPREF1068_00816; -.
DR PATRIC; fig|997884.3.peg.826; -.
DR eggNOG; COG3866; Bacteria.
DR HOGENOM; CLU_004997_0_0_10; -.
DR Proteomes; UP000003089; Unassembled WGS sequence.
DR GO; GO:0004557; F:alpha-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR026444; Secre_tail.
DR NCBIfam; TIGR04183; Por_Secre_tail; 1.
DR PANTHER; PTHR42970; PECTATE LYASE C-RELATED; 1.
DR PANTHER; PTHR42970:SF1; PECTATE LYASE C-RELATED; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR SMART; SM00060; FN3; 2.
DR SMART; SM00560; LamGL; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF51126; Pectin lyase-like; 1.
DR PROSITE; PS50853; FN3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003089};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..971
FT /note="Fibronectin type-III domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003726070"
FT DOMAIN 470..558
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 971 AA; 106520 MW; 2665011CDA1FE667 CRC64;
MLYKKLITTL LLPLCMGTMY AQQLAFPGAE GYGRFAKGAR ASESPEIYHV TNLDDSGKGS
LRDAVSQPNR IIVFDVAGVI KLKSRLVFSK NLTIAGQTAP GEGVVVYGNG VSFSAAENII
VRYLRIRMGI GGTSGADAAG IANGGNMIFD HVSATWGLDE NFSINWDSKG FEPYNITIQN
SIIGQGIMVH ACGGLIQTNG GVTLYRNLYI DNKTRNPKVK GLNQFVNNVV YNWGEGGAYI
LGDTEASSWG VITNNYFIKG PVEGTKAFTR AKAAFQVYQK GNMIDYNKDG ILNGYEATED
DYRRDASNPE SENVTFIKSI DEFDYSDYDR RKLVDGEKVV VTTIPEKHPV IEGETTAAEA
YDWIINRVGA SLPVRDEADN YMIDELLSLG TKGALLSGES ELGLPNGVGN IFDGEKMLDT
DNDGMPDVWE DANGLDKNNP NDALLMAENG YLNIENYVNS ITAPMPYVKY PTNLQLTSLS
TDYLSFKWVN NAPESTSVIL EYSIDNKDFT SISLAPGTTT HKLESLAPNT TYYIRLKTVN
GEKESLYTST QEFATRGIPA PPIASVNPIP GNETTITDYT SVRLSWENKT GAWAGALSYT
VYLGKSVEDM DVVLTASTAN VVTVNVEAAT TYYWRVDAKN LLGDCKGDVW SFTTGTKPER
GKVAYYSFNE TEGTILENMY GENATAKDFT PLWVKGIQNN AAQFDKANAA FVQEHYDALT
LGNESFSIEL WFKSAGGSVD WYLLHKGSHA TNSYEGATGK WFGIQYQKNS KNDRLTWAID
DNVTKTDINV TGATTKYFNN EWVHLVCVRD VEEKQLKMYA NGILVASGAD KTGDIGTIER
MAIGNCNTAY ENGFQGLMDE LTIYNEALTA EEVSDHYKQG TSTHIENIIT PNTGCAYPMP
FADDFYIPVM GAEDLTAQVS VMNTAGQTVY QAQVIIQGGI AHVANVGFLP KGYYVYTLKI
DQRILVGKIV K
//
