ID   I9SFG8_9BACE            Unreviewed;       677 AA.
AC   I9SFG8;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 44.
DE   RecName: Full=Signal transduction histidine kinase internal region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF1068_00389 {ECO:0000313|EMBL:EIY54676.1};
OS   Bacteroides nordii CL02T12C05.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=997884 {ECO:0000313|EMBL:EIY54676.1, ECO:0000313|Proteomes:UP000003089};
RN   [1] {ECO:0000313|EMBL:EIY54676.1, ECO:0000313|Proteomes:UP000003089}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CL02T12C05 {ECO:0000313|EMBL:EIY54676.1,
RC   ECO:0000313|Proteomes:UP000003089};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA   Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA   Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA   Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Bacteroides nordii CL02T12C05.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EIY54676.1}.
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DR   EMBL; AGXS01000003; EIY54676.1; -; Genomic_DNA.
DR   RefSeq; WP_007483225.1; NZ_JH724314.1.
DR   AlphaFoldDB; I9SFG8; -.
DR   STRING; 997884.HMPREF1068_00389; -.
DR   GeneID; 69504429; -.
DR   PATRIC; fig|997884.3.peg.407; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG3275; Bacteria.
DR   HOGENOM; CLU_397758_0_0_10; -.
DR   Proteomes; UP000003089; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003089};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        433..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          472..548
FT                   /note="Signal transduction histidine kinase internal
FT                   region"
FT                   /evidence="ECO:0000259|Pfam:PF06580"
FT   DOMAIN          570..671
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|Pfam:PF02518"
SQ   SEQUENCE   677 AA;  78604 MW;  33FFD155F38832AD CRC64;
     MGSKTIKGFA IICLFLCING CGEHTQTGEA IKKNTQTDSL EKQARDSLFA NNTYARNLLR
     SGMAKATDSL TFYRLMNHYV KACFASSDFD SVLYYNQIIA RFCREASDSP SIHDMKANVY
     NMTGNYWIQK AEPDSSLAYY RKAYEEQRLG NNVFNLPELC FNLADASNHL GNYADGAFYY
     RRGLFLCDSL QLPDTKKWTV YWGLGQTYME LRDFELSNYY YELAGNYYQE MNPYEKWGYL
     NNRGNHFYYK KDYLQAEYYI SRGLHVLDDY PQMIFERNLS KGNLGELYML NGKLDSAQIY
     LNDSYRYFTE MNNRSALYYI ETQLIELALK QGDISRAGRL IANATPGVHI DANMINIRNQ
     YLEHYYERTG DYRRAYEYLK RDVALNDSIR NERVRTRVAE LDMRYRQDTI VMRRELVIGR
     QTSEMRVLRL TSFIWAIGCI VLIAALSVFY WLMKKKRAFM QERHLNQISR LRMENIRNHI
     SPHFTFNVLN REISHLKGSE EDREGLVGLA KLLRKSLELT EKLSIPLREE LDFVRTYINL
     EQTSLGSDFI LTLSIDDKLN TEQIIIPSMI IQIPVENAMK HGLAGIEGEK RLTISVISEG
     NGVRIIIVDN GRGYLPHMIS PSRGTGTGLK VLYQTIQLLN QKNKGEKICF EIKKLADGQQ
     TGTCVSVYIP YKYSYDL
//