ID I9SSX7_HELPX Unreviewed; 303 AA.
AC I9SSX7;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Geranyltranstransferase {ECO:0000313|EMBL:EJB59634.1};
DE EC=2.5.1.10 {ECO:0000313|EMBL:EJB59634.1};
GN Name=ispA {ECO:0000313|EMBL:EJB59634.1};
GN ORFNames=HPHPH36_1048 {ECO:0000313|EMBL:EJB59634.1};
OS Helicobacter pylori Hp H-36.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992044 {ECO:0000313|EMBL:EJB59634.1, ECO:0000313|Proteomes:UP000005932};
RN [1] {ECO:0000313|EMBL:EJB59634.1, ECO:0000313|Proteomes:UP000005932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hp H-36 {ECO:0000313|EMBL:EJB59634.1,
RC ECO:0000313|Proteomes:UP000005932};
RA Blanchard T.G., Czinn S.J., McCracken C., Abolude K., Maroo A.,
RA Santana-Cruz I., Tallon L.J., Ficke F.W.F.;
RT "Genome sequence of Helicobacter pylori Hp H-36.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJB59634.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKOL01000007; EJB59634.1; -; Genomic_DNA.
DR RefSeq; WP_000070319.1; NZ_AKOL01000007.1.
DR AlphaFoldDB; I9SSX7; -.
DR PATRIC; fig|992044.3.peg.1016; -.
DR Proteomes; UP000005932; Unassembled WGS sequence.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:EJB59634.1}.
SQ SEQUENCE 303 AA; 34226 MW; 85FE0127EFB291E6 CRC64;
MSNPNLSFYR NECERFESFL KNHYLHLEGF HPYLEKAFFE MVLNGGKRFR PKLFLAVLCS
LVGKKDYLNQ QTEYFKIALS IECLHTYSLI HDDLPCMDNA SLRRNHPTLH AKYDETTAVL
IGDALNTYSF ELLSNALLES HIIVELVKIL SANGGIKGMI LGQALDCYFE NTPLNLEQLT
FLHEHKTAKL ISTSLMMGLV ASGINDEELF KWLQAFGLKM GLCFQVLDDI IDVTQDEKES
GKTTHLDGAK NSFVNLLGLE KASGYAHTLK TEVLNDLNAL KPAYPLLQEN LNALLNTLFK
GKT
//
