ID I9Y4Z2_HELPX Unreviewed; 321 AA.
AC I9Y4Z2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=CobW/HypB/UreG, nucleotide-binding domain protein {ECO:0000313|EMBL:EJC23520.1};
GN ORFNames=HPHPP4D_0565 {ECO:0000313|EMBL:EJC23520.1};
OS Helicobacter pylori Hp P-4d.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992103 {ECO:0000313|EMBL:EJC23520.1, ECO:0000313|Proteomes:UP000004286};
RN [1] {ECO:0000313|EMBL:EJC23520.1, ECO:0000313|Proteomes:UP000004286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hp P-4d {ECO:0000313|EMBL:EJC23520.1,
RC ECO:0000313|Proteomes:UP000004286};
RA Blanchard T.G., Czinn S.J., McCracken C., Abolude K., Maroo A.,
RA Santana-Cruz I., Tallon L.J., Ficke F.W.F.;
RT "Genome sequence of Helicobacter pylori Hp P-4d.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJC23520.1}.
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DR EMBL; AKQE01000002; EJC23520.1; -; Genomic_DNA.
DR RefSeq; WP_001124310.1; NZ_AKQE01000002.1.
DR AlphaFoldDB; I9Y4Z2; -.
DR PATRIC; fig|992103.3.peg.552; -.
DR Proteomes; UP000004286; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 220..310
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 321 AA; 36072 MW; BA283B1F1EA341C0 CRC64;
MPKIPITLIT GFLGSGKTSF LSEYLNQIDH QGVALIINEI GQAALDQRIL SVQYCGEKML
YLNAGCVCCN KRLDLVESLK ATLNNYEWRG EILKRVIIET TGLANPAPIL WTILSDVFLG
AHFEIQSVVA CVDVLNAKTH LTNNEAKEQI VFADSVLLTK TDLQNDSAAL MKLKERIQSL
NPSAEIFDKK NIDYESFFLR KNGARNFMPR MPKDSHSQGF ETLSISFEGA MEWSAFGIWL
SLLLHQYGTQ ILRIKGIIDI GSDLLVSING VMHVIYPPKH ILKDRNGSNL VFIMRHLERE
KILNSLKGFK DFLGIKGFET P
//
