ID J0IU90_HELPX Unreviewed; 327 AA.
AC J0IU90;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase {ECO:0000313|EMBL:EJB29165.1};
DE EC=4.2.1.- {ECO:0000313|EMBL:EJB29165.1};
GN Name=pseB {ECO:0000313|EMBL:EJB29165.1};
GN ORFNames=HPNQ4228_1313 {ECO:0000313|EMBL:EJB29165.1};
OS Helicobacter pylori NQ4228.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992025 {ECO:0000313|EMBL:EJB29165.1, ECO:0000313|Proteomes:UP000004299};
RN [1] {ECO:0000313|EMBL:EJB29165.1, ECO:0000313|Proteomes:UP000004299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NQ4228 {ECO:0000313|EMBL:EJB29165.1,
RC ECO:0000313|Proteomes:UP000004299};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJB29165.1}.
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DR EMBL; AKNT01000004; EJB29165.1; -; Genomic_DNA.
DR RefSeq; WP_001873921.1; NZ_AKNT01000004.1.
DR AlphaFoldDB; J0IU90; -.
DR PATRIC; fig|992025.3.peg.1297; -.
DR Proteomes; UP000004299; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR InterPro; IPR020025; PseB.
DR NCBIfam; TIGR03589; PseB; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:EJB29165.1}.
FT DOMAIN 7..280
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 327 AA; 36726 MW; 2165B8B0A64C7815 CRC64;
MLDNQTILIT GGTGSFGKRF VRKVLDTTNA KKIIVYSRDE LKQSEMAMEF NDPRMRFFIG
DVRDLERLNY ALEGVDICIH AAALKHVPIA EYNPLECIKT NIMGASNVIN ACLKNAISQV
IALSTDKAAN PINLYGATKL CSDKLFVSAN NFKGSSQTQF SVVRYGNVVG SRGSVVPFFK
KLVQNKASEI PITDIRMTRF WITLDEGVSF VLKSLKRMHG GEIFVPKIPS MKMTDLAKAL
APNIPTKIIG IRPGEKLHEV MIPKDESHLA LEFEDFFIIQ PTISFQTPKD YTLTRLHEKG
QKVAPDFEYS SHNNNQWLEP DDLLKLL
//
