ID J0KHF7_9BURK Unreviewed; 485 AA.
AC J0KHF7;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase {ECO:0000313|EMBL:EJE53070.1};
GN ORFNames=PMI14_02329 {ECO:0000313|EMBL:EJE53070.1};
OS Acidovorax sp. CF316.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=1144317 {ECO:0000313|EMBL:EJE53070.1, ECO:0000313|Proteomes:UP000004811};
RN [1] {ECO:0000313|EMBL:EJE53070.1, ECO:0000313|Proteomes:UP000004811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF316 {ECO:0000313|EMBL:EJE53070.1,
RC ECO:0000313|Proteomes:UP000004811};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJE53070.1}.
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DR EMBL; AKJX01000099; EJE53070.1; -; Genomic_DNA.
DR RefSeq; WP_007853664.1; NZ_AKJX01000099.1.
DR AlphaFoldDB; J0KHF7; -.
DR PATRIC; fig|1144317.3.peg.2019; -.
DR Proteomes; UP000004811; Unassembled WGS sequence.
DR GO; GO:0018480; F:5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity; IEA:InterPro.
DR GO; GO:1901023; P:4-hydroxyphenylacetate catabolic process; IEA:InterPro.
DR CDD; cd07093; ALDH_F8_HMSADH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR011985; DH_HpaE.
DR NCBIfam; TIGR02299; HpaE; 1.
DR PANTHER; PTHR43720; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43720:SF2; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000004811}.
FT DOMAIN 16..471
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 242
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 485 AA; 51774 MW; FFDB9A601BE780BD CRC64;
MRIDHLIEGK PVAGREYFET VNPATQEVLA EVASGGAAEV NAAVAAAKDA FPAWAGLPAP
ERAKLIRKLG DLIAAEVPQI AATETRDTGQ VIAQTGKALI PRAADNFYYF AEMCTRVDGH
TYPTPTHLNY TLFHPVGVCA LISPWNVPFM TSTWKVAPAL AFGNTAVLKM SELSPLTAAR
LGQLALEAGI PAGVLNVVHG FGKEAGEPLC AHPDVRAISF TGSTATGNRI VQAAGLKKFS
MELGGKSPFV VFDDADLDRA LDAAVFMIFS NNGERCTAGS RILVQKSIYA DFAEKFAARA
RRITVGDPMD DRTIIGPMIS PAHLAKVRSY IELGPKEGAT LLCGGLGAPE LPAHLHKGNF
VRPTVFADVN NRMQIAQDEI FGPVACLIPF ADEAEAIRLA NDTQYGLSSY VWTENIGRAH
RVAAGIEAGM CFVNSQNVRD LRQPFGGTKG SGTGREGGSW SYEVFLEPKN VAVSLGSHHI
PHWGV
//
