ID J0NHS1_HELPX Unreviewed; 375 AA.
AC J0NHS1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=2-oxoglutarate oxidoreductase OorA subunit {ECO:0000313|EMBL:EJB85977.1};
DE EC=1.2.7.3 {ECO:0000313|EMBL:EJB85977.1};
GN Name=oorA {ECO:0000313|EMBL:EJB85977.1};
GN ORFNames=HPHPH9_0576 {ECO:0000313|EMBL:EJB85977.1};
OS Helicobacter pylori Hp H-9.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992062 {ECO:0000313|EMBL:EJB85977.1, ECO:0000313|Proteomes:UP000006416};
RN [1] {ECO:0000313|EMBL:EJB85977.1, ECO:0000313|Proteomes:UP000006416}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hp H-9 {ECO:0000313|EMBL:EJB85977.1,
RC ECO:0000313|Proteomes:UP000006416};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJB85977.1}.
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DR EMBL; AKPA01000002; EJB85977.1; -; Genomic_DNA.
DR RefSeq; WP_001206815.1; NZ_AKPA01000002.1.
DR AlphaFoldDB; J0NHS1; -.
DR PATRIC; fig|992062.3.peg.566; -.
DR Proteomes; UP000006416; Unassembled WGS sequence.
DR GO; GO:0047553; F:2-oxoglutarate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR32154:SF14; 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:EJB85977.1}.
FT DOMAIN 14..243
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 275..368
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 375 AA; 41505 MW; 5FA089AFBA0D6DDF CRC64;
MREIISDGNE LVAKAAIEVG CRFFGGYPIT PSSDIMHAMS VALPKCGGHF IQMEDEISGI
SVSLGASMSG TKSMTASSGP GISLKVEQIG YSFMAEIPLV IADVMRSGPS TGMPTRVAQG
DVNFLKHPIH GDFKAVALAP ASLEEAYTET VRAFNLAEML MTPVFLLMDE TVGHMYGKVQ
IPDLEEVQKM IINRKEFLGD KKDYKPYGVA QDEPAVLNPF FKGYRYHVSG LHHGPIGFPT
EDAKIGGDLI DRLFNKIESK QDIINENEEM DLEGAEIIII AYGSVSLAVK EALKDYNKES
KQKVGFFRPK TLWPSPAKRL KEIGDKYEKI LVIELNKGQY LEEIERAMQR KVHFFGQANG
RTISPKQIIA KLKEL
//
