ID   J0RY75_9EURY            Unreviewed;       377 AA.
AC   J0RY75;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Indolepyruvate ferredoxin oxidoreductase alpha and beta subunits-like protein {ECO:0000313|EMBL:EJG06486.1};
GN   ORFNames=Metli_0518 {ECO:0000313|EMBL:EJG06486.1};
OS   Methanofollis liminatans DSM 4140.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanomicrobiaceae; Methanofollis.
OX   NCBI_TaxID=28892 {ECO:0000313|EMBL:EJG06486.1};
RN   [1] {ECO:0000313|EMBL:EJG06486.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4140 {ECO:0000313|EMBL:EJG06486.1};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Lu M., Detter J.C.,
RA   Tapia R., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Spring S., Schuler E., Brambilla E.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanofollis liminatans DSM 4140.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM001555; EJG06486.1; -; Genomic_DNA.
DR   RefSeq; WP_004037762.1; NZ_CM001555.1.
DR   AlphaFoldDB; J0RY75; -.
DR   STRING; 28892.Metli_0518; -.
DR   HOGENOM; CLU_709064_0_0_2; -.
DR   OrthoDB; 116011at2157; -.
DR   Proteomes; UP000005095; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR045025; HACL1-like.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR   PANTHER; PTHR43710; 2-HYDROXYACYL-COA LYASE; 1.
DR   PANTHER; PTHR43710:SF6; INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA; 1.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE   4: Predicted;
KW   Pyruvate {ECO:0000313|EMBL:EJG06486.1}.
FT   DOMAIN          257..325
FT                   /note="Thiamine pyrophosphate enzyme TPP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02775"
SQ   SEQUENCE   377 AA;  39084 MW;  9496967CCBF70A90 CRC64;
     MDGGEALAAA LRLVADQIYT VPGYPVTDVA RAADAEVCVN EKVALEYALG DSLAGRRAAV
     IVKNVGMNLL ADPLVQATAQ GLIAGVVVVA GDDPLCRASQ AAEDSSYFGP LAMVPVIEPE
     TDVFASVGAA FALSERLSRV AVLRVTPDIL EAPVGPEPLV PPRTPGALAP RSLTMRGRWE
     RARAAAAAAV PPHLPGVRVV LPAVEAPEGE PERFAARGFS RGLCPHCPYH ALFTLLAERD
     LRPACDAGCS LLAMNPPYGI GVASYGLGSA VGVGARSTGV ALIGDYALIH SGINALIDVY
     EKGAPLLCIV LANNRMGMVG GHEVPDVLRY IGWAGPVVCD AADTAALRRL ILPANRPVTI
     IVRGICPGGE SHEHVEC
//