ID J0SEE2_HELPX Unreviewed; 476 AA.
AC J0SEE2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Peptidase Do family protein {ECO:0000313|EMBL:EJC33866.1};
DE EC=3.4.21.- {ECO:0000313|EMBL:EJC33866.1};
GN ORFNames=HPHPP13B_0543 {ECO:0000313|EMBL:EJC33866.1};
OS Helicobacter pylori Hp P-13b.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992107 {ECO:0000313|EMBL:EJC33866.1, ECO:0000313|Proteomes:UP000003392};
RN [1] {ECO:0000313|EMBL:EJC33866.1, ECO:0000313|Proteomes:UP000003392}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hp P-13b {ECO:0000313|EMBL:EJC33866.1,
RC ECO:0000313|Proteomes:UP000003392};
RA Blanchard T.G., Czinn S.J., McCracken C., Abolude K., Maroo A.,
RA Santana-Cruz I., Tallon L.J., Ficke F.W.F.;
RT "Genome sequence of Helicobacter pylori Hp P-13b.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJC33866.1}.
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DR EMBL; AKQI01000003; EJC33866.1; -; Genomic_DNA.
DR RefSeq; WP_000976622.1; NZ_AKQI01000003.1.
DR AlphaFoldDB; J0SEE2; -.
DR MEROPS; S01.500; -.
DR GeneID; 66521673; -.
DR PATRIC; fig|992107.3.peg.523; -.
DR Proteomes; UP000003392; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00987; PDZ_serine_protease; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011782; Pept_S1C_Do.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR PANTHER; PTHR43343; PEPTIDASE S12; 1.
DR PANTHER; PTHR43343:SF3; PROTEASE DO-LIKE 8, CHLOROPLASTIC; 1.
DR Pfam; PF13180; PDZ_2; 2.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EJC33866.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..476
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039668012"
FT DOMAIN 266..355
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 375..444
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT ACT_SITE 117
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 148
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 222
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ SEQUENCE 476 AA; 51707 MW; 44175CE4A1E60527 CRC64;
MMKKTLFISL ALALSLNAGN IQIQNMPKVK ERISVPSKED TIYSYHDSIK DSIKAVVNIS
TEKKIKNNFI GGGVFNDPFF QQFFGDLGGM IPKERMERAL GSGVIISKDG YIVTNNHVID
GADKIKVTIP GSNKEYSATL VGTDSESDLA VIRITKDNLP TIKFSDSNDI LVGDLVFAIG
NPFGVGESVT QGIVSALNKS GIGINSYENF IQTDASINPG NSGGALIDSR GGLVGINTAI
ISKTGGNHGI GFAIPSNMVK DIVTQLIKTG KIERGYLGVG LQDLSGDLQN SYDNKEGAVV
ISVEKDSPAK KAGILVWDLI TEVNGKKVKN TNELRNLIGS MLPNQRVTLK VIRDKKERTF
TLTLAERKNP NKKETISAQN GVQGQLNGLQ VEDLTQKTKR SMRLSDDVQG VLVSQVNENS
PAEQAGFRQG NIITKIEEIE VKSVADFNHA LEKYKGKPKR FLVLDLNQGY RIILVK
//
