ID J1HN20_9ACTO Unreviewed; 590 AA.
AC J1HN20;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:EJF46993.1};
DE Flags: Fragment;
GN ORFNames=HMPREF1318_2197 {ECO:0000313|EMBL:EJF46993.1};
OS Actinomyces massiliensis F0489.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1125718 {ECO:0000313|EMBL:EJF46993.1, ECO:0000313|Proteomes:UP000002941};
RN [1] {ECO:0000313|EMBL:EJF46993.1, ECO:0000313|Proteomes:UP000002941}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0489 {ECO:0000313|EMBL:EJF46993.1,
RC ECO:0000313|Proteomes:UP000002941};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJF46993.1}.
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DR EMBL; AKFT01000036; EJF46993.1; -; Genomic_DNA.
DR AlphaFoldDB; J1HN20; -.
DR eggNOG; COG1643; Bacteria.
DR Proteomes; UP000002941; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43519; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR PANTHER; PTHR43519:SF1; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EJF46993.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002941}.
FT DOMAIN 103..258
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 322..495
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 45..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 590
FT /evidence="ECO:0000313|EMBL:EJF46993.1"
SQ SEQUENCE 590 AA; 61128 MW; E1049893B192FC38 CRC64;
MVAPSISFEN VDLDKEAVDG PISVRSTTDL GAGYDRSRCG VRPISATLEA DVGSRRTKDE
GHGEPGTGHN EPVDSSAPDP LARLLAAPPR LPAREALPRL RELLADDPGH GIVVTAPPGT
GKTTLVPPLV AHALTTPEDG GRVIVTQPRR IAARAAARRL ADLLDEPLGN TVGYAVRGER
EAGPHTRIEV VTAGLLLRRL QADPDLPGVA AVVLDEVHER SLESDLLLTL LLDARALRED
LVIIAMSATA DLDRLPTMLG AGSPDAAAAD SAADGGNSTD GPGLAPEAPI VSVTGSLHPL
QEVWAPPPSR TPRLGPHGVP REFLAHVAAT AQRALTERTG DALVFLPGAR EVEDVVSRLH
GSVPESVDVL PLHGRLSARA QDAALAPSPP GHRRVVVATN VAESSLTVPG VRVVVDAMLT
RQPRLDVARG MSGLVTVGAS RAEGVQRAGR AGREGPGVVY RCCTPTDWAR APQAPVPEIL
SADLTRLVLE LAVWGAPDGA GLTWLDPPPA PAMEAARTAL QRLGLLEDDA EADGAAAAVT
VLGRAVARIP ADARLARALL TARGTVGARR AAEGTALLSA ELRAPGGDLT
//
