ID J1S3V2_9ACTN Unreviewed; 438 AA.
AC J1S3V2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Class I SAM-dependent methyltransferase {ECO:0000313|EMBL:QTZ92336.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:QTZ92336.1};
DE SubName: Full=Cyclopropane-fatty-acyl-phospholipid synthase {ECO:0000313|EMBL:EJJ05512.1};
GN ORFNames=SU9_013320 {ECO:0000313|EMBL:QTZ92336.1}, SU9_18171
GN {ECO:0000313|EMBL:EJJ05512.1};
OS Streptomyces auratus AGR0001.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1160718 {ECO:0000313|EMBL:EJJ05512.1};
RN [1] {ECO:0000313|EMBL:EJJ05512.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGR0001 {ECO:0000313|EMBL:EJJ05512.1};
RX PubMed=22965094; DOI=10.1128/JB.01155-12;
RA Han X., Li M., Ding Z., Zhao J., Ji K., Wen M., Lu T.;
RT "Genome Sequence of Streptomyces auratus Strain AGR0001, a Phoslactomycin-
RT Producing Actinomycete.";
RL J. Bacteriol. 194:5472-5473(2012).
RN [2] {ECO:0000313|EMBL:QTZ92336.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AGR0001 {ECO:0000313|EMBL:QTZ92336.1};
RA Wen M.-L., Han X.-L., Xiong J.;
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC {ECO:0000256|ARBA:ARBA00010815}.
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DR EMBL; AJGV01000106; EJJ05512.1; -; Genomic_DNA.
DR EMBL; CP072931; QTZ92336.1; -; Genomic_DNA.
DR RefSeq; WP_006605164.1; NZ_CP072931.1.
DR AlphaFoldDB; J1S3V2; -.
DR STRING; 1160718.SU9_18171; -.
DR KEGG; sauh:SU9_013320; -.
DR PATRIC; fig|1160718.3.peg.3674; -.
DR eggNOG; COG2230; Bacteria.
DR HOGENOM; CLU_026434_6_2_11; -.
DR OrthoDB; 9782855at2; -.
DR Proteomes; UP000009036; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003333; CMAS.
DR InterPro; IPR020803; PKS_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43667; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR PANTHER; PTHR43667:SF1; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR Pfam; PF02353; CMAS; 1.
DR PIRSF; PIRSF003085; CMAS; 1.
DR SMART; SM00828; PKS_MT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Methyltransferase {ECO:0000313|EMBL:QTZ92336.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009036};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:QTZ92336.1}.
FT DOMAIN 160..404
FT /note="Polyketide synthase methyltransferase"
FT /evidence="ECO:0000259|SMART:SM00828"
SQ SEQUENCE 438 AA; 48637 MW; 69691B65BF40E3FE CRC64;
MAYAAGRLTK LAEEVLGAPL PVRIRAWDRS ESGPPGAPTL VIRHRRALRR MLFRPGELGL
ARAWVAGDLD IEGDLYAALD LLAGLIWERP GSPGPQRAAV LRALARPEMR AAARQLLTLA
GAPVPPAAPA EEVRRRRGPL HTLRRDKEAI SHHYDVGNDF YALVLGPSMV YSCAYWGTAD
QGVATLEDAQ RDKLDLICRK LGLQEGMRLL DVGCGWGSMV LHAVREYGVR AVGITLSEEQ
ATFARKRVAE AGLADRIEIR VQDYREVHDE PFDAISSVGM AEHVGRTQYA EYAGALYSLL
KPGGRLLNHQ IARRPVADEE AYHVDEFIDR YVFPDGELAP LGRTVGQLEE AGFEVRDVEA
IREHYARTLR QWVVNLEQHW EQAARLTSPG RARVWRLYMA ASALSFERNR IGVNQVLAVK
TPEGGDSALP LRTRTWSA
//
