ID J1ZRQ6_9ACTN Unreviewed; 261 AA.
AC J1ZRQ6;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Cobalamin biosynthesis protein {ECO:0000313|EMBL:EJJ04281.1};
DE Flags: Fragment;
GN ORFNames=SU9_24252 {ECO:0000313|EMBL:EJJ04281.1};
OS Streptomyces auratus AGR0001.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1160718 {ECO:0000313|EMBL:EJJ04281.1};
RN [1] {ECO:0000313|EMBL:EJJ04281.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGR0001 {ECO:0000313|EMBL:EJJ04281.1};
RX PubMed=22965094; DOI=10.1128/JB.01155-12;
RA Han X., Li M., Ding Z., Zhao J., Ji K., Wen M., Lu T.;
RT "Genome Sequence of Streptomyces auratus Strain AGR0001, a Phoslactomycin-
RT Producing Actinomycete.";
RL J. Bacteriol. 194:5472-5473(2012).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CobD/CbiB family.
CC {ECO:0000256|ARBA:ARBA00006263}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJJ04281.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJGV01000150; EJJ04281.1; -; Genomic_DNA.
DR AlphaFoldDB; J1ZRQ6; -.
DR STRING; 1160718.SU9_24252; -.
DR eggNOG; COG1270; Bacteria.
DR HOGENOM; CLU_054212_1_2_11; -.
DR OrthoDB; 9811967at2; -.
DR UniPathway; UPA00148; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0048472; F:threonine-phosphate decarboxylase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR HAMAP; MF_00024; CobD_CbiB; 1.
DR InterPro; IPR004485; Cobalamin_biosynth_CobD/CbiB.
DR PANTHER; PTHR34308; COBALAMIN BIOSYNTHESIS PROTEIN CBIB; 1.
DR PANTHER; PTHR34308:SF1; COBALAMIN BIOSYNTHESIS PROTEIN CBIB; 1.
DR Pfam; PF03186; CobD_Cbib; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 240..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 261
FT /evidence="ECO:0000313|EMBL:EJJ04281.1"
SQ SEQUENCE 261 AA; 26188 MW; 44F65F26DC4B367B CRC64;
MRGEHAGYAC GAALGFLGDL IAADPRRGHP VAAFGRAAAA VERRLWRDHR GYGAAHAVLC
AGGAAAGAAL LVRAVRGTAP SPSPLRGSAG VALTAATVWA VLGGTSLGRE AQAVGGALAA
GDLEVARERL PHLCGRDPQA LDGPQMARAV VESVAENTSD AVVGALVWGA LGGVPGLVAF
RAVNTLDAMV GHKSARYRRF GWAAARLDDL AGWPGSRLTA ALTVLAGPGR RAALRAWRAD
GGAHPSPNAG PVEASFAGAL G
//
