ID J2SY95_9FLAO Unreviewed; 1449 AA.
AC J2SY95;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Heavy metal efflux pump, cobalt-zinc-cadmium {ECO:0000313|EMBL:EJL70597.1};
GN ORFNames=PMI13_02760 {ECO:0000313|EMBL:EJL70597.1};
OS Chryseobacterium populi.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=1144316 {ECO:0000313|EMBL:EJL70597.1, ECO:0000313|Proteomes:UP000007509};
RN [1] {ECO:0000313|EMBL:EJL70597.1, ECO:0000313|Proteomes:UP000007509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF314 {ECO:0000313|EMBL:EJL70597.1,
RC ECO:0000313|Proteomes:UP000007509};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJL70597.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKJY01000053; EJL70597.1; -; Genomic_DNA.
DR RefSeq; WP_007844627.1; NZ_AKJY01000053.1.
DR PATRIC; fig|1144316.3.peg.2778; -.
DR OrthoDB; 9758757at2; -.
DR Proteomes; UP000007509; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004763; CusA-like.
DR InterPro; IPR003423; OMP_efflux.
DR NCBIfam; TIGR00914; 2A0601; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 1.
DR Pfam; PF02321; OEP; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 345..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 878..897
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 904..922
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 928..954
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 975..996
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1008..1034
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1046..1063
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT COILED 1212..1246
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1449 AA; 160678 MW; AADF820BC25BA812 CRC64;
MLTKIIGFSV KNKLIIALLV FGLIGVGAYQ VTQLPIDAVP DITNNQVQVI TTAPSFGATD
IERLVTFPIE QSNSNISGLK EIRSFSRFGL SLVTIVFDDD IDIYWARQQV AERLQQVQNQ
IPPDIGTPTL GPISTGLGEI YQYVVRPKKG YESKYDITEL RTLQDWIVRR QLLGVKGVAE
VSSFGGKLKQ YEISVNPDKL NAYGITITDV FDALKTNNQN TGGSYIEKGP TVLYIRSEGL
VGNLDDIKNI SISTKNNGVP LFIRDIAEVR YGYATRFGAM TYNDNGEVSG AIVMMLKGEN
SSEVIKNVKA KILQIQKTLP EGVVIEPFLD RTKMVNNAIG TVEKNLMEGA LIVVFVLVLF
LGNFRAGLLV ASVIPLAMLF AICTMNLFGV SGNLMSLGAL DFGLIIDGAV IIVESVMHQF
THNAKFRKTI SISKQEMDTI VIDSAGKMMN SAVFGQIIIL IVYLPILTLQ GIEGKMFKPM
AQTVAFALLG AFLLSLTYIP MMSSIILSKK IGHKMNFSDR LMAKVETLYR KTLLKVLRVP
ITIFSIVIVL FILAVVVLSR MGGEFIPSLE EGDFAVDTRV LSGSNIKTTI ESTQKAAHIL
KTRFPEVQKV VTKIGSGEVP TDPMPMDASD MMVILKDKSE WTSAKSFPEL SDKMSKALED
VPGITVGFQY PVQMRFNELM TGARQDVVLK IFGENLETLV TNANQLGKII NTVKGTQNLY
IEPVSGLSQV IIQYNRPVIA QYHLSIGDIN RVINTAFAGQ STGLVFEGEK RFDMVVRLNS
NDRKNLDDVK NLLVPTPSGN QIPLSQLANI DIKDGPNQIQ RENGQRRIVV GFNIKNRDVQ
GIVEELQTKV DQQLKLPPGY YVTYGGSFEN LKNAKSRLMI AVPIALILIF VLLFLAFNSV
KESLLIYTAI PLSIIGGVFL LAARGMPFSI SAGVGFIALF GVAVLNGIVL ISEFNRLYKS
GIKNIVRIVV DGGEARLRPV LMTAFVASLG FIPMALSNGA GAEVQRPLAT VVIGGLLIAT
LLTLFVLPLL YVTIEKGFKM KNIRKNIVTP ALIIFFVLTG SVMNSQAKIT LNEAVDIALK
NNRGLKNEKL KSEYAKALIK TSLDIPQTGI SADYGQINSA YRDMKFGISQ SITFPTVYKR
QKNLYTEEWK KSELNISLKE YQLKKGVTLT FYNILYWQEK ERILNESLDF YSQFLDKATL
RLKSGESNIL EKATAANQKS AIEIQIKQVQ QELRTLQLQL QWLLNSETEL IPGGERILSL
SGLQNDVSGN PSLKILEQQK NIAAQQTAWE KSKLLPGLQF AYNLNSFRGM GADDKIYNSS
PQFHSFQLGV SVPIFSGSQK ARIESSKIAE SVSQNDWQNA QFTLNNQYKK LSEIQQKNLE
IVSQYEKYEL KNANTILETA QKQFINGEIN YLEFVMLANQ AISIKNNYTD AVWNLNESIV
ELEYITLNQ
//
