ID J2Z3S1_9LACO Unreviewed; 329 AA.
AC J2Z3S1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Tagatose 1,6-diphosphate aldolase {ECO:0000256|HAMAP-Rule:MF_00734};
DE EC=4.1.2.40 {ECO:0000256|HAMAP-Rule:MF_00734};
DE AltName: Full=D-tagatose-1,6-bisphosphate aldolase {ECO:0000256|HAMAP-Rule:MF_00734};
DE AltName: Full=Tagatose-bisphosphate aldolase {ECO:0000256|HAMAP-Rule:MF_00734};
GN Name=lacD {ECO:0000256|HAMAP-Rule:MF_00734};
GN ORFNames=A11Y_8655 {ECO:0000313|EMBL:EJN55093.1};
OS Loigolactobacillus coryniformis subsp. coryniformis CECT 5711.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Loigolactobacillus.
OX NCBI_TaxID=1185325 {ECO:0000313|EMBL:EJN55093.1, ECO:0000313|Proteomes:UP000007271};
RN [1] {ECO:0000313|EMBL:EJN55093.1, ECO:0000313|Proteomes:UP000007271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT5711 {ECO:0000313|Proteomes:UP000007271};
RA Rodriguez J.M.;
RT "Complete Genome Sequence of Lactobacillus coryniformis CECT5711.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-tagatofuranose 1,6-bisphosphate = D-glyceraldehyde 3-
CC phosphate + dihydroxyacetone phosphate; Xref=Rhea:RHEA:22948,
CC ChEBI:CHEBI:57642, ChEBI:CHEBI:58694, ChEBI:CHEBI:59776; EC=4.1.2.40;
CC Evidence={ECO:0000256|ARBA:ARBA00000567, ECO:0000256|HAMAP-
CC Rule:MF_00734};
CC -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC phosphate: step 2/2. {ECO:0000256|ARBA:ARBA00005191, ECO:0000256|HAMAP-
CC Rule:MF_00734}.
CC -!- SIMILARITY: Belongs to the aldolase LacD family.
CC {ECO:0000256|ARBA:ARBA00008679, ECO:0000256|HAMAP-Rule:MF_00734}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJN55093.1}.
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DR EMBL; AKFP01000086; EJN55093.1; -; Genomic_DNA.
DR RefSeq; WP_003680114.1; NZ_AKFP01000086.1.
DR AlphaFoldDB; J2Z3S1; -.
DR STRING; 1185325.A11Y_8655; -.
DR PATRIC; fig|1185325.3.peg.2393; -.
DR UniPathway; UPA00704; UER00716.
DR Proteomes; UP000007271; Unassembled WGS sequence.
DR GO; GO:0009024; F:tagatose-6-phosphate kinase activity; IEA:InterPro.
DR GO; GO:0009025; F:tagatose-bisphosphate aldolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0019512; P:lactose catabolic process via tagatose-6-phosphate; IEA:UniProtKB-UniRule.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR HAMAP; MF_00734; LacD; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR InterPro; IPR005927; Tag_1.6-dipho_adolase.
DR PANTHER; PTHR39340; SULFOFRUCTOSEPHOSPHATE ALDOLASE; 1.
DR PANTHER; PTHR39340:SF1; SULFOFRUCTOSEPHOSPHATE ALDOLASE; 1.
DR Pfam; PF01791; DeoC; 1.
DR SMART; SM01133; DeoC; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lactose metabolism {ECO:0000256|ARBA:ARBA00022736, ECO:0000256|HAMAP-
KW Rule:MF_00734};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00734};
KW Reference proteome {ECO:0000313|Proteomes:UP000007271}.
SQ SEQUENCE 329 AA; 36846 MW; E226CE849FD4D911 CRC64;
MNAEKYKHLE ALSTEAGIID ALAIDQRGSL KKMLAASSPD GEKTGYDIIK FKTTISEELT
PFASAILLDP EYGLPAAKAR AKNAGLLMSY EKTGYDTTQP GRFPDLLEDW SVRRLKEIGV
DAVKFLLYYD ADESEEINNR KRAFIERVGA EADEYNLPFF LELVSYDANM DDVKGEKYAK
VKPHKVIELT KEFSQPKYRV TVLKVEVPVN MAFVEGYTDT GVLPVYTRTE ALGYFKAQSD
ATNLPFIFLS AGVTNELFLK ELQFAKEAGS TFNGVLCGRA TWKPGVTPFA KDGVQAGREW
MKTEGKKNIE RLNEVLAKTA TSWKEKVRQ
//
