ID J3HZQ9_9BRAD Unreviewed; 232 AA.
AC J3HZQ9;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=PMI42_06135 {ECO:0000313|EMBL:EJN10538.1};
OS Bradyrhizobium sp. YR681.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=1144344 {ECO:0000313|EMBL:EJN10538.1, ECO:0000313|Proteomes:UP000007272};
RN [1] {ECO:0000313|EMBL:EJN10538.1, ECO:0000313|Proteomes:UP000007272}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YR681 {ECO:0000313|EMBL:EJN10538.1,
RC ECO:0000313|Proteomes:UP000007272};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJN10538.1}.
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DR EMBL; AKIY01000261; EJN10538.1; -; Genomic_DNA.
DR RefSeq; WP_008140715.1; NZ_AKIY01000261.1.
DR AlphaFoldDB; J3HZQ9; -.
DR PATRIC; fig|1144344.3.peg.5701; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000007272; Unassembled WGS sequence.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EJN10538.1};
KW Protease {ECO:0000313|EMBL:EJN10538.1};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 25..213
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 232 AA; 25029 MW; 40D7729637924A00 CRC64;
MKVLMVITSH DQLGNTGRKT GFWLEELAAP YYVFKDSGAE ITLASPKGGR PPLDPKSNEP
EFRTDLTVRF EKDAAAEAQL DKTVRLDSVR QEDFDTLFYP GGHGPMWDLA EDRNSVKLIE
SFLAAGKTIA VVCHSTGALR HVKTPDGKPL VQGKEVTGFT NGEEEDVGLT KIVPFLVEDE
MLKLGAVFSK TANWGVHVVS AGQLITGQNP HSSGPAAQTL LAALKQKGKS AA
//
