ID J3KE44_COCIM Unreviewed; 78 AA.
AC J3KE44;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=COX assembly mitochondrial protein {ECO:0000256|RuleBase:RU364104};
GN ORFNames=CIMG_04737 {ECO:0000313|EMBL:EAS33713.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS33713.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- FUNCTION: Required for mitochondrial cytochrome c oxidase (COX)
CC assembly and respiration. {ECO:0000256|RuleBase:RU364104}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|RuleBase:RU364104}.
CC -!- SIMILARITY: Belongs to the CMC family. {ECO:0000256|ARBA:ARBA00007347,
CC ECO:0000256|RuleBase:RU364104}.
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DR EMBL; GG704914; EAS33713.3; -; Genomic_DNA.
DR RefSeq; XP_001245296.1; XM_001245295.2.
DR AlphaFoldDB; J3KE44; -.
DR STRING; 246410.J3KE44; -.
DR GeneID; 4564795; -.
DR KEGG; cim:CIMG_04737; -.
DR VEuPathDB; FungiDB:CIMG_04737; -.
DR InParanoid; J3KE44; -.
DR OMA; PYNANCE; -.
DR OrthoDB; 2783622at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR013892; Cyt_c_biogenesis_Cmc1-like.
DR PANTHER; PTHR22977; COX ASSEMBLY MITOCHONDRIAL PROTEIN; 1.
DR PANTHER; PTHR22977:SF1; COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG; 1.
DR Pfam; PF08583; Cmc1; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|RuleBase:RU364104};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|RuleBase:RU364104};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU364104};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU364104};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT REGION 57..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 78 AA; 9184 MW; 4043BD357D9FA57E CRC64;
MHSHLHTKDN INCEEIMNAL DECHARGFLY KAVGGCNEVK REVNRCLGAE RFKRAKKNRD
TARENRSRIE QIWKDRGE
//
