ID J3KEK9_COCIM Unreviewed; 325 AA.
AC J3KEK9;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 22-FEB-2023, entry version 47.
DE SubName: Full=HIRA-interacting protein 5 {ECO:0000313|EMBL:EAS33934.3};
GN ORFNames=CIMG_04958 {ECO:0000313|EMBL:EAS33934.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS33934.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SIMILARITY: Belongs to the NifU family.
CC {ECO:0000256|ARBA:ARBA00006420}.
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DR EMBL; GG704914; EAS33934.3; -; Genomic_DNA.
DR RefSeq; XP_001245517.1; XM_001245516.2.
DR AlphaFoldDB; J3KEK9; -.
DR STRING; 246410.J3KEK9; -.
DR GeneID; 4564436; -.
DR KEGG; cim:CIMG_04958; -.
DR VEuPathDB; FungiDB:CIMG_04958; -.
DR InParanoid; J3KEK9; -.
DR OMA; AIMEHYM; -.
DR OrthoDB; 168791at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR Gene3D; 3.30.300.130; Fe-S cluster assembly (FSCA); 1.
DR Gene3D; 3.30.1370.70; Scaffold protein Nfu/NifU, N-terminal domain; 1.
DR InterPro; IPR034904; FSCA_dom_sf.
DR InterPro; IPR014824; Nfu/NifU_N.
DR InterPro; IPR036498; Nfu/NifU_N_sf.
DR InterPro; IPR001075; NIF_FeS_clus_asmbl_NifU_C.
DR PANTHER; PTHR11178; IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED; 1.
DR PANTHER; PTHR11178:SF1; NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL; 1.
DR Pfam; PF08712; Nfu_N; 1.
DR Pfam; PF01106; NifU; 1.
DR SMART; SM00932; Nfu_N; 1.
DR SUPFAM; SSF117916; Fe-S cluster assembly (FSCA) domain-like; 1.
DR SUPFAM; SSF110836; Hypothetical protein SAV1430; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT DOMAIN 83..177
FT /note="Scaffold protein Nfu/NifU N-terminal"
FT /evidence="ECO:0000259|SMART:SM00932"
FT REGION 302..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 35431 MW; 8E766F4094B4D7B7 CRC64;
MAVRTASRSL SQAISRSQSA SGVFASPPRW MIFTPRTVYT QAARIPVITS SRSRHRPTLL
RQHQPVAAQM PANVPANNRT IFIQTEVTPN ADALKFIPNY PVLPENFPAP FLEYLSPRST
LAAPHPSPLA AKLLNVDGVS SVFYGPDFIT ITKAGDANWA HIKPEVFSLI TEAVTSGEQL
VNTVAVAEGA QAGQEGSGEE AVEYNEEDEE VVGMINELLE TRIRPAIQED GGDIEFRGFK
DGNVMLKLRG ACRTCDSSTV TLKNGIESML MHYIEEVKSV TQVIDEEEEV ALKEFERFEE
KLRQQKGPGA TASTVGKGSL DTADA
//
