ID J3KFP5_COCIM Unreviewed; 690 AA.
AC J3KFP5;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=CAMK protein kinase {ECO:0000313|EMBL:EAS34465.3};
GN ORFNames=CIMG_05489 {ECO:0000313|EMBL:EAS34465.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS34465.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704914; EAS34465.3; -; Genomic_DNA.
DR RefSeq; XP_001246048.2; XM_001246047.2.
DR AlphaFoldDB; J3KFP5; -.
DR STRING; 246410.J3KFP5; -.
DR GeneID; 4564864; -.
DR KEGG; cim:CIMG_05489; -.
DR VEuPathDB; FungiDB:CIMG_05489; -.
DR InParanoid; J3KFP5; -.
DR OMA; IARCEWA; -.
DR OrthoDB; 5395166at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24346; MAP/MICROTUBULE AFFINITY-REGULATING KINASE; 1.
DR PANTHER; PTHR24346:SF82; SERINE_THREONINE-PROTEIN KINASE MARK-A-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EAS34465.3};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW Transferase {ECO:0000313|EMBL:EAS34465.3}.
FT DOMAIN 363..672
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 74859 MW; 0035D116AC35DB1F CRC64;
MVERNPSRTE PHPVNTGATT LGLDASPRTS LTTTSTTIST KHPSTASASL PEQPQPGCPP
NRLVGQAPTT PNFNVAPHDD SRLLTNLLPN EPSTPLQRPP ALSVRTDFGD TRIMAPGSQP
DLDAPLRASL SSTSLPHRTS SLRAALAAPH SSTGSLSPGS IFSSPQLAAL TDITPLPSPI
QGNSPWRCGS YQSLPRSPST ASYRGSTFSL KSLDPTRPPR SSSGQRRGYD TAPGGQDQTP
AEKEVHIRVP QNGHARNRSL SEYVPPALHV PAVLKSPSNS SNGVSCVSPS PRRTVQNKLH
REEYLAVQRG LTIPHAHPPS PPSTRRGEES SENGMAPGSL GPSLSSAQVY NVKSVRTQQP
RRYRMIRQLG QGTFSQVVLA VREGLPNVEF NGTHDIPAQP RLVAVKVVEY GPAGGADEER
VEVSLKREVD ILKSIHHPSI TQLKAFGSEQ KRALLVLDYC PGGDLFEFAS QAPKALSPPL
IRRIFAELVA AVRYLHQNQI VHRDIKLENV LINVPTAVMQ DIGEWESYPR SIVTLTDLGL
SRRIPQPPES PLLHTRCGSE DYAAPEILMG QPYDGRSTDG WALGVLLYAI VENRLPFDPL
PGTRGDPAKL RARTPHRIAR CEWSWYRYGD DDGEWDPAKG AALDGAQLCV QGLLKRSSRR
MQLDDIAKTE WVSKAIKVPG GLKRGDIEGP
//
