ID J3KLD3_COCIM Unreviewed; 446 AA.
AC J3KLD3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 13-SEP-2023, entry version 43.
DE RecName: Full=DUF1682 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CIMG_02431 {ECO:0000313|EMBL:EAS37077.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS37077.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704911; EAS37077.3; -; Genomic_DNA.
DR RefSeq; XP_001248660.1; XM_001248659.2.
DR AlphaFoldDB; J3KLD3; -.
DR STRING; 246410.J3KLD3; -.
DR GeneID; 4566076; -.
DR KEGG; cim:CIMG_02431; -.
DR VEuPathDB; FungiDB:CIMG_02431; -.
DR InParanoid; J3KLD3; -.
DR OMA; FDGFVWA; -.
DR OrthoDB; 1386451at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IEA:InterPro.
DR InterPro; IPR012879; CCDC47.
DR PANTHER; PTHR12883; ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED; 1.
DR PANTHER; PTHR12883:SF0; PAT COMPLEX SUBUNIT CCDC47; 1.
DR Pfam; PF07946; CCDC47; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 76..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 10..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 373..407
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 409..439
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 50337 MW; BEE7EC5F2F5B946B CRC64;
MSGIFQNILK GGSKDSASGG SQQDDSDFAD FSATSQQPVA SASTASAPGS TIAAPVMSVP
YTKWYRVWER TSPKDFMQEA FVLPFILFIV IFHVWGTRKN RRKAKAWAQA HIPVLHNEFA
VVGYRGVRRG AILKDLSSSA DLVIDDNLLR EKAANEFTTY ATGRQNVAFV DVTIQLVKRY
NPMFILGDSI AGMFFDSLTP QTEKIEVTAY SFDGKEKDLV PAPPAEKEQL GKGMNSTHDG
FVFAIVNKTA MRRLREDRYD VSLTFTKDNP KLPEWVTVMS ESAEITDTIL TNELIKAIED
AGDLFEYLII TDQPADKPAK VEEAVSRKRS ILSMRVPSST SSTAYASSLP LFHLFIRLTD
RLAASAHFRP EVLRKLRATR EEEVRKLRRA TEDEKAEERK LAAEKVKKEG RDRLLRGMSA
EEQRKYLEKE KEREAKKEMK KYSRRA
//
