ID J3KMK8_MOUSE Unreviewed; 105 AA.
AC J3KMK8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Serine protease inhibitor, Kunitz type 5 {ECO:0000313|Ensembl:ENSMUSP00000135911.2};
GN Name=Spint5 {ECO:0000313|Ensembl:ENSMUSP00000135911.2,
GN ECO:0000313|MGI:MGI:3651687};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000135911.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000135911.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000135911.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000135911.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000135911.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; J3KMK8; -.
DR SMR; J3KMK8; -.
DR ProteomicsDB; 369491; -.
DR Ensembl; ENSMUST00000180193.2; ENSMUSP00000135911.2; ENSMUSG00000074593.12.
DR AGR; MGI:3651687; -.
DR MGI; MGI:3651687; Spint5.
DR VEuPathDB; HostDB:ENSMUSG00000074593; -.
DR GeneTree; ENSGT00940000168105; -.
DR InParanoid; J3KMK8; -.
DR OMA; LTFVCEP; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; J3KMK8; Protein.
DR Bgee; ENSMUSG00000074593; Expressed in embryonic cell in blastocyst and 11 other cell types or tissues.
DR ExpressionAtlas; J3KMK8; baseline and differential.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00109; Kunitz-type; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR PANTHER; PTHR10083; KUNITZ-TYPE PROTEASE INHIBITOR-RELATED; 1.
DR PANTHER; PTHR10083:SF217; PROTEIN CBG23496; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 1.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..105
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003771897"
FT DOMAIN 49..99
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
SQ SEQUENCE 105 AA; 11736 MW; 79128218921BE115 CRC64;
MAGPGIRLAL WLLTFAMSLS MLSSSLLYPA GVRSQLCESG HLGAKTVICN QPVKKGFCSF
TFYRYYFNPE SALCESFIFT GCGGNRNNFK TKYLCEVRCI HVEKD
//
