ID J3S4Z4_CROAD Unreviewed; 357 AA.
AC J3S4Z4;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Retinoic acid-induced protein 3-like {ECO:0000313|EMBL:AFJ51147.1};
OS Crotalus adamanteus (Eastern diamondback rattlesnake).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus.
OX NCBI_TaxID=8729 {ECO:0000313|EMBL:AFJ51147.1};
RN [1] {ECO:0000313|EMBL:AFJ51147.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Venom gland {ECO:0000313|EMBL:AFJ51147.1};
RX PubMed=23025625; DOI=10.1186/1471-2164-13-312;
RA Rokyta D.R., Lemmon A.R., Margres M.J., Aronow K.;
RT "The venom-gland transcriptome of the eastern diamondback rattlesnake
RT (Crotalus adamanteus).";
RL BMC Genomics 13:312-312(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JU175623; AFJ51147.1; -; mRNA.
DR AlphaFoldDB; J3S4Z4; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR InterPro; IPR017978; GPCR_3_C.
DR PANTHER; PTHR14511; G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5; 1.
DR PANTHER; PTHR14511:SF7; RETINOIC ACID-INDUCED PROTEIN 3; 1.
DR Pfam; PF00003; 7tm_3; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..266
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|Pfam:PF00003"
FT REGION 328..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 40198 MW; A77BE8DBAB8C02F7 CRC64;
MATTEPPQGC GNIHNDYFFL CDTNAYWGII LEALAAAGAI ATIILILVLL CFINKVQDNA
KRSLIPIQFL FLLGTLGIFG LTFAFIIRLN EQTAPTRFFL FGVLFALCFS CLLAHALDLV
RLVRGRRPFS ALGLLIMVFG LTIVQAIIAI QYVVVNITAL KKLHNVMDPE SQRDFVLILI
YVFFLMFLLC VVSMFVFCGS YKRWKRHGFY LFLTALVSIA IWVAWIAILM HGISDLGEPS
EWNDPLIGVT LIVNGWAFLL LYAIPELCVL TAPRKPGDYP QENNTCQPKG MKKTYGVENQ
GYAQEDNTQE ENTGSYVPYS THFQLKNLEP QQEFTIPRPK TRPSPYQGYS GGKDIKK
//
