ID J3S5D9_CROAD Unreviewed; 530 AA.
AC J3S5D9;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member {ECO:0000256|RuleBase:RU369103};
OS Crotalus adamanteus (Eastern diamondback rattlesnake).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus.
OX NCBI_TaxID=8729 {ECO:0000313|EMBL:AFJ51867.1};
RN [1] {ECO:0000313|EMBL:AFJ51867.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Venom gland {ECO:0000313|EMBL:AFJ51867.1};
RX PubMed=23025625; DOI=10.1186/1471-2164-13-312;
RA Rokyta D.R., Lemmon A.R., Margres M.J., Aronow K.;
RT "The venom-gland transcriptome of the eastern diamondback rattlesnake
RT (Crotalus adamanteus).";
RL BMC Genomics 13:312-312(2012).
CC -!- FUNCTION: Multifunctional protein that is involved in the regulation of
CC many processes. {ECO:0000256|RuleBase:RU369103}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|RuleBase:RU369103}.
CC -!- SIMILARITY: Belongs to the ANP32 family.
CC {ECO:0000256|ARBA:ARBA00025777, ECO:0000256|RuleBase:RU369103}.
CC -!- SIMILARITY: Belongs to the TBCE family.
CC {ECO:0000256|ARBA:ARBA00006286}.
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DR EMBL; JU176344; AFJ51867.1; -; mRNA.
DR AlphaFoldDB; J3S5D9; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR CDD; cd17044; Ubl_TBCE; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR045081; AN32.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR044079; Ubl_TBCE.
DR PANTHER; PTHR11375; ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32; 1.
DR PANTHER; PTHR11375:SF0; ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF14580; LRR_9; 1.
DR Pfam; PF14560; Ubiquitin_2; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS51450; LRR; 2.
PE 2: Evidence at transcript level;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614,
KW ECO:0000256|RuleBase:RU369103}; Nucleus {ECO:0000256|RuleBase:RU369103};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 27..71
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
SQ SEQUENCE 530 AA; 60259 MW; 675F0B970FBB7BA5 CRC64;
MSDTIPSDAV GRRILCNEEY GTVLYVGKVP PTTGIWLGVE WDNHERGKHN GSHEGIQYFK
CRHPTGGSFI RPNKANFGVD FLSAVKKKYG LNENEHDPES ETALSLVIGS KTVETVGFDS
IKEKLRQLNT LSDISVDACA VSLAGQEEEI RKSCPNIRQI NLSKNLLSSW KEVLAIACQT
ENLETLNLSE NKMKFPPVLP PASQTFCKLR VLALNQTGVT WTEVLLCATG WPALEELYLA
SNSISLLKSP IDVLQNLKWL DLSNNQLSDE NQLHLIADLP RLERLILSNN EIYSMYFPDA
TFGYKTRMFP SLTHLILKDN RIAKWSVINE LDKLQKLESF DCRNNPLMES DKNVETVKQL
IIAKIGQLKF LNKSQIFPEE RRGAELDYRK KYGIDWLKAG GNQDPNKNKP SEEFLAAHPR
FQLLCDLYGA PEDGELKREQ PFSLKNQLLT LTFKCPDKAD QKPIEKKLPD SMTIQKVKGL
LYRLIKNSGS ELKLSYESSK MKGKEFELDN DLKPLQFYSI ENEDCILVRW
//
