ID J4GMI3_9APHY Unreviewed; 377 AA.
AC J4GMI3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=TFIIS N-terminal domain-containing protein {ECO:0000259|PROSITE:PS51319};
GN ORFNames=FIBRA_02142 {ECO:0000313|EMBL:CCM00115.1};
OS Fibroporia radiculosa.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Fibroporiaceae; Fibroporia.
OX NCBI_TaxID=599839 {ECO:0000313|EMBL:CCM00115.1, ECO:0000313|Proteomes:UP000006352};
RN [1] {ECO:0000313|EMBL:CCM00115.1, ECO:0000313|Proteomes:UP000006352}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TFFH 294 {ECO:0000313|EMBL:CCM00115.1,
RC ECO:0000313|Proteomes:UP000006352};
RX PubMed=22247176; DOI=10.1128/AEM.06745-11;
RA Tang J.D., Perkins A.D., Sonstegard T.S., Schroeder S.G., Burgess S.C.,
RA Diehl S.V.;
RT "Short-read sequencing for genomic analysis of the brown rot fungus
RT Fibroporia radiculosa.";
RL Appl. Environ. Microbiol. 78:2272-2281(2012).
CC -!- FUNCTION: Transcription factor involved in RNA polymerase II
CC transcription regulation. May function in both SPT15/TBP post-
CC recruitment and recruitment steps of transcription.
CC {ECO:0000256|ARBA:ARBA00037349}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the IWS1 family.
CC {ECO:0000256|ARBA:ARBA00037992}.
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DR EMBL; HE796965; CCM00115.1; -; Genomic_DNA.
DR RefSeq; XP_012179398.1; XM_012324008.1.
DR AlphaFoldDB; J4GMI3; -.
DR STRING; 599839.J4GMI3; -.
DR GeneID; 24095026; -.
DR HOGENOM; CLU_045275_2_0_1; -.
DR InParanoid; J4GMI3; -.
DR OrthoDB; 12240at2759; -.
DR Proteomes; UP000006352; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR46010; PROTEIN IWS1 HOMOLOG; 1.
DR PANTHER; PTHR46010:SF1; PROTEIN IWS1 HOMOLOG; 1.
DR Pfam; PF08711; Med26; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000006352}.
FT DOMAIN 201..279
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 1..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 377 AA; 42860 MW; 31DFFF21108971AC CRC64;
MERDKGHLDL EEQIFGRDSD DELSSPEEDE PPPRRNVRAS SGIPDDAESS GDSGDEYVQE
KAAAKVKQSR RRSRRVAEEG ERQPKQRKRK RKQLDEIDLS QLPPEQASKL RLDMQIEAIL
KPKKSSKSRR KKKDDEDVLD RYADEEVSRL REAMLSAAQD DDQSNREKLP ATAKLRMLSQ
VMEVLRKNSL SQSITDNNLL EGVRRWLEPL PDRSLPALDI QKEFFPILKK MEYIDSSALK
ESGLGRVVIF YTKSKRVTAD IARHANDLIS AWSRPIIKRS ASYRDRIVPT AQTGDGEGAR
GGERLNTILA RARETDKNRV RKNAVMIPQR ELGSYTVAPK PNAGFGKGSM SVDVDIERRK
RGAERLRSLT RKMATKS
//
