ID J4K8L7_STROR Unreviewed; 322 AA.
AC J4K8L7;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Putative TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit {ECO:0000313|EMBL:EJP21241.1};
GN ORFNames=HMPREF1125_0771 {ECO:0000313|EMBL:EJP21241.1};
OS Streptococcus oralis SK304.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1161421 {ECO:0000313|EMBL:EJP21241.1, ECO:0000313|Proteomes:UP000006745};
RN [1] {ECO:0000313|EMBL:EJP21241.1, ECO:0000313|Proteomes:UP000006745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK304 {ECO:0000313|EMBL:EJP21241.1,
RC ECO:0000313|Proteomes:UP000006745};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJP21241.1}.
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DR EMBL; ALJN01000016; EJP21241.1; -; Genomic_DNA.
DR RefSeq; WP_000105348.1; NZ_ALJN01000016.1.
DR AlphaFoldDB; J4K8L7; -.
DR PATRIC; fig|1161421.3.peg.1313; -.
DR Proteomes; UP000006745; Unassembled WGS sequence.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 14..311
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 322 AA; 35142 MW; 3EA7637F0D994840 CRC64;
MSTLDKNLLL EMFRKMEEIR RMDLKIAQLV KKGKVPGMTH FSVGEEAANV GAMLALNPDD
LITSNHRGHG QAIAKGIDLN GMMAEILGKY TGTCKGKGGS MHIADLDAGN LGANGIVGGG
MGIAVGAALS QQMQHTDKIV VCFFGDGATN EGVFHEAVNM ASIWKLPVIF YCINNGYGIS
ADIKKMTNVE HIHHRSAAYG IPGMFIEDGN NVIDVYEGFK KAVDHVRGGN GPVLIESVTY
RWLGHSSSDP GKYRTREEVE LWKQKDPIEN LRKYLIENTI ASAEELEEIQ AQVKEAVEAS
VKFAEESPFP PLESAFEDIY AD
//
