ID J4KLV4_BEAB2 Unreviewed; 1383 AA.
AC J4KLV4;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Peptide synthetase {ECO:0000313|EMBL:EJP62859.1};
GN ORFNames=BBA_08246 {ECO:0000313|EMBL:EJP62859.1};
OS Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)
OS (Tritirachium shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=655819 {ECO:0000313|EMBL:EJP62859.1, ECO:0000313|Proteomes:UP000002762};
RN [1] {ECO:0000313|EMBL:EJP62859.1, ECO:0000313|Proteomes:UP000002762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2860 {ECO:0000313|EMBL:EJP62859.1,
RC ECO:0000313|Proteomes:UP000002762};
RX PubMed=22761991; DOI=10.1038/srep00483;
RA Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., Shang Y.,
RA St Leger R.J., Zhao G.P., Wang C., Feng M.G.;
RT "Genomic perspectives on the evolution of fungal entomopathogenicity in
RT Beauveria bassiana.";
RL Sci. Rep. 2:483-483(2012).
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DR EMBL; JH725181; EJP62859.1; -; Genomic_DNA.
DR RefSeq; XP_008601565.1; XM_008603343.1.
DR STRING; 655819.J4KLV4; -.
DR GeneID; 19891258; -.
DR HOGENOM; CLU_255202_0_0_1; -.
DR InParanoid; J4KLV4; -.
DR OrthoDB; 2487657at2759; -.
DR Proteomes; UP000002762; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020459; AMP-binding.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 1.
DR PRINTS; PR00154; AMPBINDING.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002762}.
FT DOMAIN 227..609
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 670..746
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT DOMAIN 949..1346
FT /note="Condensation"
FT /evidence="ECO:0000259|Pfam:PF00668"
FT COILED 858..885
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1383 AA; 151725 MW; 34E7975D95B28CA4 CRC64;
MAITQVRPAE VPRTNLPYYD LATHNEVDAK QVPRQYQSST LKASPIVKSP TSILKAFAAF
VAGVTDLEAV AFIANYADID DANPQRLLAT ASIPGNSKPR VFTSDHIEVA TFPTENLDEN
NLDFEIEIVF DVAPAAKASR AFCLRVEPLE DGSIADLTLS IDSKHGHSVL VYHMLELVSK
YLADSATQAP ETKMSNLNYP LKLWKAPILK TDSHIKQNYP SLMHGAFERR VLECPDRIAV
EAVADDSFTV RKWTYLQLNA DAEGLAEELL LMERTIDWTP AYKNQRAIPL FLPAGPEFYI
TVIAMLKAGF AVCSLPMDAP PQRLLDIVED TKSSVVIGVG SVPFPSVSLN DDSEAAESLK
KLTWVDITEF TNWRSNFTVD LQTPVSHHLP TEEDLAYILY TSGSTGKPKG VLISHSMATC
GVHGHAEVFE PLPAGPELRW LQFAMPTFDL SLMELFVTLG YGGTVCSAER SLMLSDIERA
VNFFNATALF TVASMATLLR PKALPTLTTI VSGGEALTKY AIDNFAYDAP REPNSKPKRV
INIYGPTEAT MCATFENAAL GTRGSIAGTV FSCASVVLVD ANSSDDLIQV PMGLTGEIVF
GGPMVGYGYM NRPEETAKAF TTGLDLGSVY RTGDKGRIVF DPKGEPKLEI LGRLNMEQVK
LNTRRVELGE IESTIAKVEA VREVATVVLK GSFLAAYVAV RENFGDVTDE SVISQCREVA
SEGLPAWMRP VEYIVVPKVP RTSSGKVDRK TLQNAAVEDF GNSITQKQAI NDNLTYQGTV
DLKDTDSVSA MLEHILMAIL GEGATDIANS PLALTTYGLD SLRSMKLLQE LRRQAVEGLA
IKDVLVGQNF ASVVKSILEL HLDQLKEAEE AAAAKNDELI EIEDEEEILF LPLAAKLKHF
DHTCRRKCVE ALNIPSEDIV EVLPATGLQT RVLSSIEESA DILKVSKPWV EHYPYLVPEH
IDADRLEAAV IQALKGRDAF RTVWVQVEHP LAPYAQCVLS PNSPHAKLPI LRMECPVYDE
RPGSLWHRTV DNAQKSAEET FGLHSLGSVT SFVRSADKKH CVVVFSVFHA IYDGMSLQAL
RRDIAEAYHG LPISSTGKSG VRVPVEEHLK SDWLGTSMFW AQRMAGVASF KAGDRVLKTE
GAVFTTVNTN VGIASESLEC TFSTGELFAK AKSEGLFTPM AVIQAAWSMT LAQTLVGDEA
APKYDVQFGS VFHGRHTADS LDAFALMLDG LPTRVSFEKN KNLTHREICS RMFKQYTDTL
GFTEMPCPSI QFARTTRRFD SSVILQTFPA PDIDVDMNGL PAFNRANDKV TPWKETSSDT
PILIEMWPGV NKTEDKLSIR CSYSQGLLVT FNKALTQVLN NPDGVFDVVQ SATSPQDAMD
CSP
//
