ID J5GKK3_STROR Unreviewed; 367 AA.
AC J5GKK3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EJP20960.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:EJP20960.1};
GN ORFNames=HMPREF1125_0501 {ECO:0000313|EMBL:EJP20960.1};
OS Streptococcus oralis SK304.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1161421 {ECO:0000313|EMBL:EJP20960.1, ECO:0000313|Proteomes:UP000006745};
RN [1] {ECO:0000313|EMBL:EJP20960.1, ECO:0000313|Proteomes:UP000006745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK304 {ECO:0000313|EMBL:EJP20960.1,
RC ECO:0000313|Proteomes:UP000006745};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJP20960.1}.
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DR EMBL; ALJN01000016; EJP20960.1; -; Genomic_DNA.
DR RefSeq; WP_001140857.1; NZ_ALJN01000016.1.
DR AlphaFoldDB; J5GKK3; -.
DR PATRIC; fig|1161421.3.peg.1054; -.
DR Proteomes; UP000006745; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EJP20960.1}.
FT DOMAIN 3..293
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 367 AA; 41065 MW; 1AA1B2506C1B7027 CRC64;
MAKTVYIAGL GLIGASMALG IKRDHPDYEI LGYNRSQASR DIALKEGMID RATDDFASFA
PLADVIILTL PIKQTIAFIK ELADLYLKEG VIISDAGSTK SAIVDAAEKY LASKPVRFVG
AHPMAGSHKT GAASADVNLF ENAYYIFTPS SLTSQDTLEE MKDLLSGLHA RFIEIEAKEH
DRVTSQISHF PHILASGLME QTAVYAQEHE MTRRFAAGGF RDMTRIAESD PGMWTSILLS
NRETILERIA DFKERLDEVG QAISKGEEEK IWNFFNQARE QRQAMEIHKR GGVDSSYDLY
VDVPDEEDVI LRILELLRGT SLVNIHINEE NREDVHGILQ ISFKNAQDLE RAERLISENT
DYTVVIK
//
