ID   J6F6Z2_TRIAS            Unreviewed;       500 AA.
AC   J6F6Z2;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   RecName: Full=Calpain catalytic domain-containing protein {ECO:0000259|PROSITE:PS50203};
GN   ORFNames=A1Q1_00754 {ECO:0000313|EMBL:EJT52849.1};
OS   Trichosporon asahii var. asahii (strain ATCC 90039 / CBS 2479 / JCM 2466 /
OS   KCTC 7840 / NBRC 103889/ NCYC 2677 / UAMH 7654) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Trichosporonales; Trichosporonaceae; Trichosporon.
OX   NCBI_TaxID=1186058 {ECO:0000313|EMBL:EJT52849.1, ECO:0000313|Proteomes:UP000002748};
RN   [1] {ECO:0000313|EMBL:EJT52849.1, ECO:0000313|Proteomes:UP000002748}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 90039 / CBS 2479 / JCM 2466 / KCTC 7840 / NCYC 2677 / UAMH
RC   7654 {ECO:0000313|Proteomes:UP000002748};
RX   PubMed=23104369; DOI=10.1128/EC.00237-12;
RA   Yang R.Y., Li H.T., Zhu H., Zhou G.P., Wang M., Wang L.;
RT   "Draft genome sequence of CBS 2479, the standard type strain of
RT   Trichosporon asahii.";
RL   Eukaryot. Cell 11:1415-1416(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJT52849.1}.
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DR   EMBL; ALBS01000013; EJT52849.1; -; Genomic_DNA.
DR   RefSeq; XP_014183923.1; XM_014328448.1.
DR   AlphaFoldDB; J6F6Z2; -.
DR   GeneID; 25984268; -.
DR   KEGG; tasa:A1Q1_00754; -.
DR   VEuPathDB; FungiDB:A1Q1_00754; -.
DR   HOGENOM; CLU_671189_0_0_1; -.
DR   OrthoDB; 1472030at2759; -.
DR   Proteomes; UP000002748; Unassembled WGS sequence.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001300; Peptidase_C2_calpain_cat.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS50203; CALPAIN_CAT; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00239};
KW   Protease {ECO:0000256|PROSITE-ProRule:PRU00239};
KW   Thiol protease {ECO:0000256|PROSITE-ProRule:PRU00239}.
FT   DOMAIN          157..500
FT                   /note="Calpain catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50203"
FT   ACT_SITE        166
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00239"
FT   ACT_SITE        428
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00239"
FT   ACT_SITE        454
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00239"
SQ   SEQUENCE   500 AA;  53696 MW;  C45A6294E725F8E4 CRC64;
     MNHPNVPVEV TYPIGPNTGT VKDFIDSGKI PVWNGTRDLL NGQLPANLGD ASTSKAGATG
     QFGPEQGTNS NAAVFRYHGS VVARQYNPDL QLNLSIGAAD YEGRKLDLTA QPDLPLPNPD
     RQLRCEYAYE HVLGGNGTTP KGALWALEGY VDLVAADVRQ GGIGDCGMGA AVQALAAGGW
     TRYLTRMFLK RFDTPNAGDR NIVAVFRRDG KVQPVLIDDQ LPTLRNANPN CWQYPGFQPV
     NDAAYPDVTK PTPIFFMPLF EKVSPASAAS GLRGEPFTPT VRATLTPQAF AKFLDANADW
     KSATGYTGYA GLEGVNPSYV LAAITGGNPS WVWRQRPGFD GPIIAAIARC MQGTAPCVVS
     TTNAQLEGLG TKDSTGALWL APNQQPAYIP GETSGLTATD TNGVTFTVID FDNLKDGKSS
     VFSWVSGHAY AFAWTRGTRW PIQDLLSPRI KFLNPWGVNP ESWPGSNGKG QWDDPAELTS
     SFRTFLESVS GVFTVTDMPA
//