ID J7GB79_9CRYP Unreviewed; 117 AA.
AC J7GB79;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 22-FEB-2023, entry version 30.
DE RecName: Full=Transcription initiation factor IIA subunit 2 {ECO:0000256|PIRNR:PIRNR009415};
GN Name=tfIIA-S {ECO:0000313|EMBL:AFP65670.1};
GN ORFNames=CMESO_526 {ECO:0000313|EMBL:AFP65670.1};
OS Chroomonas mesostigmatica CCMP1168.
OG Nucleomorph {ECO:0000313|EMBL:AFP65670.1}.
OC Eukaryota; Cryptophyceae; Pyrenomonadales; Chroomonadaceae; Chroomonas.
OX NCBI_TaxID=1195612 {ECO:0000313|EMBL:AFP65670.1, ECO:0000313|Proteomes:UP000243348};
RN [1] {ECO:0000313|EMBL:AFP65670.1, ECO:0000313|Proteomes:UP000243348}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1168 {ECO:0000313|EMBL:AFP65670.1,
RC ECO:0000313|Proteomes:UP000243348};
RX PubMed=23042551; DOI=10.1093/gbe/evs090;
RA Moore C.E., Curtis B., Mills T., Tanifuji G., Archibald J.M.;
RT "Nucleomorph genome sequence of the cryptophyte alga Chroomonas
RT mesostigmatica CCMP1168 reveals lineage-specific gene loss and genome
RT complexity.";
RL Genome Biol. Evol. 4:1162-1175(2012).
CC -!- FUNCTION: TFIIA is a component of the transcription machinery of RNA
CC polymerase II and plays an important role in transcriptional
CC activation. {ECO:0000256|PIRNR:PIRNR009415}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR009415}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 2 family.
CC {ECO:0000256|ARBA:ARBA00007675, ECO:0000256|PIRNR:PIRNR009415}.
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DR EMBL; CP003682; AFP65670.1; -; Genomic_DNA.
DR AlphaFoldDB; J7GB79; -.
DR EnsemblProtists; AFP65670; AFP65670; CMESO_526.
DR Proteomes; UP000243348; Chromosome 3 nucleomorph.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd10014; TFIIA_gamma_C; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR Gene3D; 1.10.287.190; Transcription factor IIA gamma subunit, alpha-helical domain; 1.
DR InterPro; IPR009083; TFIIA_a-hlx.
DR InterPro; IPR009088; TFIIA_b-brl.
DR InterPro; IPR003194; TFIIA_gsu.
DR InterPro; IPR015871; TFIIA_gsu_C.
DR InterPro; IPR015872; TFIIA_gsu_N.
DR PANTHER; PTHR10966; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2; 1.
DR PANTHER; PTHR10966:SF0; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2; 1.
DR Pfam; PF02751; TFIIA_gamma_C; 1.
DR Pfam; PF02268; TFIIA_gamma_N; 1.
DR PIRSF; PIRSF009415; Hum_TFIIA_gamma; 1.
DR SUPFAM; SSF47396; Transcription factor IIA (TFIIA), alpha-helical domain; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:AFP65670.1};
KW Nucleomorph {ECO:0000313|EMBL:AFP65670.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR009415};
KW Protein biosynthesis {ECO:0000313|EMBL:AFP65670.1};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR009415};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR009415}.
FT DOMAIN 6..48
FT /note="Transcription initiation factor IIA gamma subunit N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02268"
FT DOMAIN 59..102
FT /note="Transcription initiation factor IIA gamma subunit C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02751"
SQ SEQUENCE 117 AA; 13727 MW; 8DC395C1A3ACFAAE CRC64;
MSLFQYRAST LGIQLEETLQ ELLKEGVIDL ELSDFIRKHF DKAMMYVLNK WVKDKPTIKG
KLKHYQNLDN VWSFYILSPE IRVSNHSLPV SISEPLKIVA CENKIVSEFK LEKKNEK
//
